Publications
Viral infection disrupts intestinal homeostasis via Sting-dependent NF-κB signaling in Drosophila
This paper used SYNTAX-labeled fluorescent probes for RNA FISH to highlight how viral infection affects intestinal physiology and also revealed important interactions between immune pathways, gut physiology and aging in …
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Product Literature
CUS-34-SYNTAX-200-Brochure
This SYNTAX System brochure details our Enzymatic DNA Synthesis technology and the benefits it delivers for workflow control and DNA on demand via an easy benchtop instrument …
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Product Literature
SYNTAX-96-Standard-Kits
The SYNTAX 96 Standard Kits include the reagents and consumables required for the parallel enzymatic synthesis of 96 ready-to-use DNA oligos of up to 80nt in length and are intended …
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Product Literature
CUS-18-PIS_Hi-Fidelity-Reagent-Kits-F082023
The SYNTAX 96 Hi-Fidelity Kits include the reagent and consumables required for the parallel enzymatic synthesis of 96 ready to-use DNA oligos of up to 120 nucleotides (nt) in length …
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Product Literature
SYNTAX System and Software Product Sheet
The SYNTAX System is a fully integrated automated instrument that manages the template-free enzymatic synthesis of up to 96 oligos in parallel. This benchtop system synthesizes, desalts, quantifies, and normalizes …
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Publications
DNA synthesis technologies to close the gene writing gap
Synthetic DNA is of increasing demand across many sectors of research and commercial activities. Engineering biology, therapy, data storage and nanotechnology are set for rapid developments if DNA can be …
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Publications
Assessment of enzymatically synthesized DNA for gene assembly
Phosphoramidite chemical DNA synthesis technology is utilized for creating de novo ssDNA building blocks and is widely used by commercial vendors. Recent advances in enzymatic DNA synthesis (EDS), including engineered …
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Publications
Multiplex enzymatic synthesis of DNA with single-base resolution
Enzymatic DNA synthesis (EDS) is a promising benchtop and user-friendly method of nucleic acid synthesis that, instead of solvents and phosphoramidites, uses mild aqueous conditions and enzymes. For applications such …
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Poster Presentations
Rapidly assemble genes in your laboratory using automated enzymatic oligo synthesis
A straightforward protocol combining the simplicity and speed of the SYNTAX system to commercially available kits and tools, full gene constructs can be rapidly assembled from ssDNA oligos within 3 …
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Application & Technical Notes
SARS-CoV-2 Spike Protein Mutagenesis Application Note
This Application Note demonstrates the use of primers produced with EDS technology in a pragmatic, site-directed mutagenesis strategy for the production of optimized and variant SARS-CoV-2 spike protein expression plasmids …
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Application & Technical Notes
SARS-CoV-2 Amplicon Sequencing Application Note
This Application Note demonstrates the use of primers produced via EDS technology for whole-genome amplicon sequencing and phylogenetic analysis of SARS-CoV-2 isolates using the ARTIC network protocol …
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Application & Technical Notes
Gene Assembly Application Note
This Application Note describes polymerase cycling assembly of two genes from oligos produced in-house via Enzymatic DNA Synthesis (EDS) and the benchtop SYNTAX System …
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Product Literature
NGS and Sanger Sequencing Assay Support – On-demand Printing of Same-day Oligos Flyer
This flyer details the speed and accuracy of the SYNTAX System printer and SYNTAX synthesis, processing, and labelling kits to aid NGS and Sanger sequencing workflows …
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Product Literature
qPCR Assay Support – Print Primers & Probes in a Single Day Flyer
This flyer details the speed and accuracy of the SYNTAX System printer and SYNTAX synthesis, processing, and labelling kits, aiding the optimization of qPCR assay workflows …
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Application & Technical Notes
Gene Knockout Mutagenesis Application Note
This Application Note demonstrates a gene knockout mutagenesis strategy approach to identify fungal target genes with a potential role in drug tolerance to existing antifungal compounds, using oligos produced with …
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Application & Technical Notes
smFISH Application Note
This Application Note presents the first report of viral smFISH in the gut of Drosophila melanogaster, performed with fluorophore-labeled DNA probes produced in-house with DNA Script’s Enzymatic DNA Synthesis (EDS) …
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Poster Presentations
Enzymatic DNA Synthesis (EDS) enables decentralized and same-day access to DNA for critical study, developments and diagnosis to fight SARS-CoV-2
This scientific poster, in collaboration with The Jackson Laboratory and Laboratorio de Medicine Molecular, was presented at the ESHG 2021 Conference …
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Poster Presentations
Enzymatic DNA Synthesis (EDS) Enables Rapid and Broad-Based Access to Synthetic Oligos Needed for the Genetic Analysis and Functional Characterization of the SARS-CoV-2 Virus
This scientific poster, in collaboration with the University of Helsinki and FIMM, was presented at the ASHG 2021 Conference …
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Application Highlights
Guide RNA Production Application Highlight
This Application Highlight demonstrates the guide RNAs prepared by the SYNTAX System support CRISPR/Cas9-based gene editing …
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Application & Technical Notes
Enzymatic DNA Synthesis Technical Note
This Technical Note examines Enzymatic DNA Synthesis and the core components making it the technology of choice for nucleic acid synthesis …
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Poster Presentations
Enzymatic DNA Synthesis (EDS) enables decentralized and same-day access to DNA for critical study, developments, and diagnosis to fight SARS-CoV-2.
This scientific poster, in collaboration with The Jackson Laboratory and Laboratorio de Medicine Molecular, was presented at the AGBT 2021 Conference …
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