SYNTAX System

DNA ON DEMAND
Benchtop convenience.
Same-day results.

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DNA Script introduces a new paradigm in oligo production, the SYNTAX System, powered by Enzymatic DNA Synthesis (EDS) technology to accelerate life science innovation. Designed for speed, convenience, flexibility and ease of use, the SYNTAX System enables automated nucleic acid synthesis in a benchtop solution. Researchers may now have same-day synthesis of custom oligos at the lab bench, without the need for specialized infrastructure or technical skills and increased control over molecular biology and genomics workflows.
integrated solution

Sequence in,
Ready-to-use oligos out.

SYNTAX System

<15 min setup time, plug-and-play automation.

Onboard purification, quantification and normalization of oligos.

Delayed start for convenient run timing.

SYNTAX 60-cycle Kit, 96 Oligos

EDS technology for template-free synthesis.

Complete reagent & consumables kit, including 4 inks (A, T, G, C).

SYNTAX Console Software

Easy-to-use software solution for seamlessly integrated workflow.

Centrally create, manage and share DNA design runs and results files.

benchtop advantage

Rapid Assay Optimization

The SYNTAX System rapidly produces oligos on-site for maximum productivity and convenience. Within the same day, new oligos can be designed and printed based on test results. This enables rapid, iterative oligo synthesis to accelerate assay optimization and reduce hidden costs and decreased productivity due to oligo delivery wait time.


Convenience, Control, & Dependability

The SYNTAX System can be used without specialized infrastructure, skills, or experience and offers more control over sequence information and security. In-house oligo production provides dependable supply with less risk of delays due to third-party manufacturing, logistical challenges, or extraordinary global events, like the COVID-19 pandemic.


Seamless Integration into Molecular Biology Workflows

Oligos produced by EDS have been demonstrated to meet functional performance requirements in a wide range of applications, including PCR, qPCR, mutagenesis and cloning, amplicon sequencing, variant confirmation and single guide RNA (sgRNA) construction for CRISPR/Cas9 gene editing workflows.


Pre-order with Customized iDNA 5’ Motif

EDS offers the unique ability to add a sequence to the 3′-end of existing, native, single-stranded DNA. Use this unique feature to include a fixed 5′-motif—such as a primer or protein binding site, promoter sequence, restriction enzyme recognition site, adapter, or barcode—in all or a subset of oligos in a batch. The SYNTAX Console Software lets you easily design and order custom synthesis plates.

system capabilities
    Synthesize up to
    96 oligos in parallel

    4 inks – A, T, G and C
 


    200-300 pmol / well
    Normalized to 1-5 uMol
    70-150 uL final volume / well

    Fully automated:
    Sequence in – oligos out
 


    <15 min hands-on time
    6 hr for 20-mers
    13 hr for 60-mers

    Scarless, molecular biology
    ready-to-use oligos
    Default 5’-phosphate


    15-60 nt de novo oligo synthesis
    Customizable iDNA length of 15-40 nt

ordering

Ready. Set. Go.

Cat. No. Product Description
100296 SYNTAX System
(with standard 12-month warranty)
100094 SYNTAX System
(with standard 12-month warranty and 2nd year service agreement)
100134 SYNTAX 60-cycle kit, 96 oligos
100274 SYNTAX 60-cycle Custom iDNA kit, 96 oligos, pack of 4

Order your SYNTAX System today

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