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General & Administration

Position summary

The successful candidate provides accounting and financial oversight for our legal entities, and is primarily responsible for the completeness, accuracy, and compliance of all financial records for multiple legal entities and Consolidated accounts. This person is a business partner with multiple internal functions and our external auditors and is a key resource for setting up and maintaining new legal entities and business processes. You will lead the Accounting function at a global level and will report to Thibaut, our current Finance Associate Director.

In this key role for our business’s success, your responsibilities will include:

  1. Direct global accounting activities for the French and US entities, lead day to day accounting duties, ensure accurate and timely closings as well as external and internal reporting and audits.
  2. Drive and ensure high standards of financial processes and internal controls are established, implemented, and well-maintained on an on-going basis.
  3. Create and sustain a culture of continuous improvement to improve the effectiveness and efficiency of accounting operations.
  4. Ensuring the company meets all its requirements relative to tax and regulatory obligations

In this role, you will be:

  • Be in charge of developing a growing team of 3+ employees based in France and in the US, including GL, AR & AP sub-functions in their scope
  • Implement a consolidated accounting for the Group in accordance with IFRS standards
  • Build new local teams when the time arrives
  • Supervise monthly, quarterly and annual close
  • Maintain consistency of the global Chart of Accounts
  • Ensure the application and development of globally harmonized accounting processes, policies and controls, properly documented
  • Reinforce synergies, global leverage and segregation of duties inside the Accounting team
  • Lead the preparation of local statutory accounts in accordance to local GAAPs
  • Implement in-house the production of a consolidated accounting in accordance with IFRS (currently externalized)
  • Work in coordination with the Finance Management team to ensure accuracy and relevance of the analytical accounting
  • Supervise and support the local teams on audit processes
  • Work with external advisors to ensure the company meets and maintains all compliance requirements across all the relevant taxes, customs and obligations, minimizing fiscal and regulatory risk
  • Lead the enhancement of our global ERP, Oracle NetSuite, acting as project manager to external IT providers/integrators
  • Support the implementation of other tools within the Finance department

Key Qualifications/Experience

  • Master’s degree or equivalent in business, finance, accounting or related field
  • DSCG Diploma and experience in IFRS; experience in US GAAP is a plus
  • Demonstrated track record of 5+ years of experience managing accounting teams in an international company; previous audit professional experience desirable
  • Curiosity, ability to see “big picture” strategic view as well as details-oriented
  • High motivation with the capacity to work under pressure to tight deadlines
  • Operating as a team player, able to effectively establish strong working relationships across all levels and functions within a culturally and operationally diverse organization
  • Excel expertise, NetSuite is a plus
  • Fluency in English
  • Ability to manage and develop a first-in-class team

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview at the office to meet with the manager, cofounders, HR team
  3. References check
  4. Timing: 2-3 weeks
Apply now

Opportunity and challenges

We are looking to assemble a team of best-in-class, innovative and passionately impatient people. We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write.” We offer the opportunity of joining a dynamic, international, and highly skilled team in a pioneering startup. Our DNA On Demand platform not only has the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.

The Role

We are looking for an experienced Talent Acquisition Specialist to join DNA Script’s human resources team and contribute to its ambitious hiring plan (50+ positions in the US in 2022). As a Talent Acquisition Specialist, you will spearhead the company’s hiring activities in the United States, for both scientific and non-scientific positions. You will be responsible for defining positions and filling them with the best employees. Your work will require continuous relationships with operational teams, candidates and recruiting firms. Your ability to deeply understand the company’s operational needs as well as its overall strategy will help you find the best talents to support the company’s growth. You will report to the HR Manager, US.

Main Responsibilities

Hiring process

  • Develop and implement proactive Talent Acquisition strategies and build a talent pipeline of diverse and qualified talents for current and future needs
  • Be primarily responsible for executing the company’s hiring plan in the United States
  • Manage the full cycle recruitment process to ensure an exceptional candidate experience
  • Support hiring managers in writing job descriptions and scorecards
  • Source candidates through all relevant channels, including through direct approach and staffing agencies. Build a talent pool.
  • With the help of the Recruiting Coordinator, arrange interviews and interview applicants yourself
  • Design fair compensation offers in line with company policies
  • Continuously improve the hiring process

Employer brand

  • Develop and implement a strategy to improve the visibility and attractiveness of the company in the United States to attract the best talent
  • Manage university internship programs as a strategic pipeline for future hires
  • Develop and host branding events to build pipeline
  • Work in partnership with the company’s Marketing department on the outbound communication strategy for hiring purposes

Experience

  • Required: BA/BS
  • 5+ years of demonstratable experience in recruitment for scientific and/or technical positions
  • Experience in the life sciences/biotechnology/medical device/medical diagnostic/pharmaceutical industry is highly preferred
  • Experience working with a web-based ATS, preferably Greenhouse
  • Experience building talent pipelines and identifying new sources to find talent
  • Excellent interview skills and the ability to screen and select candidates
  • Experience with direct approach and staffing agencies
  • Excellent rigor and attention to details
  • Excellent organizational and reporting skills
  • Ability to multitask, prioritize and manage expectations in order to deliver on time

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview at the office to meet with the manager, cofounders, HR team
  3. References check
  4. Timing: 2-3 weeks
Apply now

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionately impatient people. We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write.” We offer the opportunity of joining a dynamic, international, and highly skilled team in a pioneering startup. Our DNA On Demand platform not only has the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.

The Role

We are looking for an experienced HR Business Partner (France), reporting to the VP of HR, who will provide advice and leverage your expertise to leaders in the areas of: Compliance, Learning & Development, Compensation & Benefits, Talent Acquisition, Workforce Planning, Performance Management, and Employee Relations.

In a context of rapid growth and intense hiring activities (at least 100 hires within 12 months), the HR Business Partner (France) contributes to the human resource strategy in support of the overall business plan and strategic direction of the company. This position is responsible for promoting a work environment that exemplifies the company’s mission and values. Additionally, this position maintains and enhances the organization’s human resources department in France by planning, implementing, and evaluating human resources policies, programs, and practices.

The HR Business Partner (France) is a strategic business partner to the leaders and their local teams, translating business strategy into a detailed HR strategy and plan. This includes using HR solutions which are both creative and thought leading. This role will support the leaders’ goals to hire, engage, develop, and retain top talent and build the organizational capabilities required for short and long-term business success.

Main Responsibilities

Cultural Leadership

  • Understand the company mission and perform all duties in line with corporate values
  • Reinforce company culture and team spirit by building bridges between DNA Script sites
  • Lead by example through the tactful expression of opinions, always with an eye towards providing productive solutions
  • Set a positive tone for employee communications

Transverse Management

  • Drive human resources operations by working efficiently across the HR team
  • Update job knowledge by participating in conferences and educational opportunities; reading professional publications; maintaining personal networks; and participating in professional organizations

Compliance

  • Ensure compliance and adherence to all applicable laws and regulation, company policies and procedures
  • Communicate changes in personnel policies and procedures and ensure proper processes are followed

Talent Acquisition

  • Collaborate with managers across the organization to help them evaluate and define their staffing needs
  • Leverage knowledge of market conditions and competitive talent landscape while driving fairness and compliance in hiring and internal job fulfillment practices and policies

Employee Experience

  • Provide excellent internal service and support on all employment related matters
  • Lead and contribute to long-term talent development, retention, and succession planning
  • Develop robust talent management plans and drive culture change initiatives to attract, retain, develop, and engage talent in critical roles
  • Regularly assess and review compensation & benefits policies to ensure competitiveness and foster employee retention

Learning & Development

  • Identify, assess and develop learning and development needs across the organization
  • Oversee the training of individuals or groups of employees
  • Coordinate management training in interviewing, hiring, terminations, promotions, performance management, and employee relations

Performance Management

  • Support and collaborate with managers by designing and implementing a strategy regarding employee growth and management
  • Facilitate performance review process that aligns company values and business objectives with employee professional and personal goals
  • Recommend and implement procedures to manage turnover
  • Consult with legal counsel as appropriate on personnel matters

Preferred experience

Experience

  • Required: Master’s degree in human resources or other relevant matter (business school, engineering school, finance degree, etc.)
  • 5+ years of experience in progressive HR roles with strong working knowledge of all key functional areas of people, process and tools, including talent acquisition, employee relations, compensation/benefits, learning and development
  • HR experience in the life sciences/biotechnology/medical device/medical diagnostic/pharmaceutical industry is highly preferred
  • Experience as a strategic business driver with credibility as a trusted advisor
  • Has a track record of positive results contributing to the growth of an organization
  • Strong ownership and hands-on mindset with the ability to handle competing priorities
  • Strong project management skills with ability to execute on short and long term deliverables
  • A strategic problem solver, who uses data and analytics to inform decision making and leadership coaching

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview at the office to meet with the manager, cofounders, HR team
  3. References check
  4. Timing: 2-3 weeks
Apply now

The position

DNA Script is looking for a talented patent engineer to join the IP Team to support the development of the company. The position will be based in our Paris headquarters. The candidate will be participating in (i) patent preparation and prosecution ; (ii) patent committee and idea sourcing ; and (iii) IP competitive intelligence actions.
The position reports to our European patent attorney, based in headquarters.

Responsibilities

  • Monitoring new ideas and finding generated by the organization
  • Drafting and filing patent applications, geographical extension
  • Patent prosecution, third party observations, opposition
  • Conduct freedom-to-operate studies on regular basis or on ad-hoc requests
  • Conduct IP landscape analysis as requested by management or operational activities
  • Raise awareness and train the Research & Development community on IP
  • Provide support with general agreements and contract upon requests

Preferred experience

Qualifications and experience

  • Has an advanced degree in Molecular Biology, Bioengineering, Molecular Genetics, Synthetic Biology, Microbiology, or a related biotechnology-relevant discipline or an advanced degree in Organic Chemistry, Nucleic Acid Chemistry or related biochemistry-relevant field;
  • Has successfully passed the CEIPI patent diploma;
  • Having at least partially passed the European Qualifying Examination is mandatory;
  • At least 2–4-year experience as a patent engineer, in biotech/ life science industry or private practice with preferable experience with clients in life sciences and biotechnology field;
  • Fluency in French and in English;
  • Strong interactive skills and collaborative attitude to work effectively in a team environment;
  • Has exceptional attention for detail and accuracy abilities;
  • Has the highest levels of personal honesty, integrity and commitment.
  • Experience in working with research and development teams and environment and/or experience in the field of DNA such as DNA synthesis or DNA sequencing would be a plus.

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview at the office to meet with the manager, cofounders, HR
  3. References check
  4. Timing: 2-3 weeks
Apply now

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionately impatient people. We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write.” We offer the opportunity of joining a dynamic, international, and highly skilled team in a pioneering startup. Our DNA On Demand platform not only has the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.

The Role

We are looking for an experienced Global Marketing Manager to lead the outbound marketing effort to build awareness of our recently launched SYNTAX platform life science markets with a focus on NGS applications. As a Global Marketing Manager, you will be expected to lead the definition, development, and execution of marketing programs involving multiple advertising channels and content from internal and external collaborators. You will also be expected to take a hands-on role in the development of new content with the ability to draft technical pieces that are compelling to the target audience. You will be expected to track and report on key performance indicators related to awareness and lead generation activities as well as ROI. You will also provide strategic input to ongoing market research and product planning activities.

Main Responsibilities:

  • History of success at market development in the genomics industry and in particular, the NGS space.
  • Understanding of strategic marketing fundamentals, tactical planning, and content development.
  • Serve as a bridge between product management, applications, and marketing communications to execute multi-channel marketing programs within a fast-paced cross-functional environment.
  • Deliver end-to-end marketing programs, engaging with internal and external stakeholders as needed to ensure predictable outcomes with accurate measurements of performance.
  • Demonstrates a bias for action and results, but with a careful attention to detail.
  • Reactive and responsive, taking full responsibility to resolve issues and regain momentum.
  • Partner with product management, marketing communications and subject matter experts to create and refine value propositions, targeted messages, marketing collateral, and content.
  • Partner with R&D and applications team to generate relevant technical application note content for NGS space
  • Development and tracking of metrics for marketing programs.
  • Analyze market and sales trends to identify opportunities and deficits. Report insights regularly to senior leadership and marketing teams.
  • Support lead management within a CRM system.
  • Identify opportunities and channels for campaigns and events to reach the target audience.
  • Engage with KOLs to facilitate development of content, webinars, seminars, testimonials.

Experience:

  • Minimum of Bachelor’s degree in life sciences or a related field, graduate degree (including PhD and/or MBA) preferred
  • 3+ years in life sciences or related industry marketing experience, with preference given to candidates with strong experience in NGS applications and workflows.
  • In depth understanding of media channels, life science publishers and genomics terminology.
  • Experience with market research, with ability to synthesize, summarize, and report analyses.
  • Experience in global, cross-functional teams.
  • Strong understanding of genomics NGS library prep and sequencing data analysis.
  • Experience with creative design and copywriting is a plus.
  • Detail-oriented with effective time and project management skills.
  • Excellent written, presentation, communication and collaboration skills with experience presenting to diverse scientific and business audiences.
  • Travel up to 25%

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview with manager, cofounders, HR and the rest of the team
  3. References Check
  4. Timing: 2-3 weeks
Apply now

The Role

Customer Service builds strong relationships with customers and serves as a liaison between customers and cross-functional groups across the company. This position will have strong communication skills and be able to remove roadblocks and provide quick resolution for customers and internal teams. They should have experience interfacing with and supporting internal and external customers and/or distributors managing order fulfillment and service operations.
The Customer Support Specialist reports to the Global Customer Service Manager in the Commercial Organization and contributes to the company’s ability to meet sales goals while providing an exceptional customer experience.

Responsibilities:

  • Validate technical aspects of orders to ensure order accuracy, completeness and technical feasibility along with company requirements for shipping and revenue recognition.
  • Review, book and manage all aspects of commercial and internal sales orders received from the business in an efficient and timely manner.
  • Provide customers with order verification, updates on delivery dates, product availability and pricing.
  • Coordinate with the service team to arrange delivery of instruments, installation reagents and other reagents and parts as required.
  • Analyzes problems, determines approach within guidelines, prepares reports and recommendations.
  • Coordinates high level activities between departments and outside parties.
  • Provide phone and email support to internal partners.
  • Monitor orders and update status to ordering parties.
  • Proactive communication to the field service team when change of order status is received.
  • File documentation promptly and assist in auditing.
  • Coordination and administrative aspects of Order Entry, Order Fulfillment, Credit/Rebill, Case/Complaint Creation, Contract and Backlog Management including but not limited to the use of multiple Systems (Netsuite,, MS Office Suite, Quickbase, Cognos, etc)
  • Works on problems of moderate scope where analysis of situations or data requires a review of a variety of factors.
  • Exercises judgment within defined policies, procedures and practices to determine appropriate action.
  • Builds productive collaborative working relationships both internally and externally.
  • Understands and applies best practices and knowledge of internal/external business challenges to improve processes or services.
  • May support Key Accounts, projects or other duties as assigned to meet business needs.

Preferred experience

  • 2 + years of customer support experience or equivalent experience in an administrative or Sales Support role preferred
  • Strong written and verbal communication skills
  • Functional knowledge of Microsoft Office and preferred experience with a CRM and/or ERP system (NetSuite a plus)
  • Familiarity with Internet commerce sites and overall comfort with technology, strongly desired.
  • Diligent, Detail Oriented, Methodical, practical, analytical with good project management skills.
  • Strong cross-team collaboration skills.
  • Experience working with a freight forwarder or strong experience with international logistics preferred.
  • Strong interpersonal and customer service skills
  • Strong desire to provide total customer support, going further to address customer core needs.
  • Experience independently solving problems and working effectively in a team environment
  • Bachelor’s Degree or equivalent work experience.

Recruitment process

  1. Phone interview with the hiring manager
  2. Day Interview with manager, cofounders, HR and the rest of the team
  3. References Check
  4. Timing: 2-3 weeks
Apply now

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionately impatient people. We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write.” We offer the opportunity of joining a dynamic, international, and highly skilled team in a pioneering startup. Our DNA On Demand platform not only has the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.

The Role

We are looking for an experienced Director of Digital Marketing and Marketing Communications to develop and grow the awareness and share of voice for DNA Script and its products. In this role you will be expected to own the creation and publication of content for digital media with a focus on establishing and developing a singular, compelling voice for DNA Script. You will be expected to take a hands-on role in the creative aspects of new content, the final formatting and publishing for various marketing channels and the management of DNA Script’s website. You will also be expected to track and report on key performance indicators related to awareness and lead generation activities as well as ROI. Finally, you will be expected to work closely with internal stakeholders, partners, and consultants to execute on marketing plan deliverables with a high degree of efficiency and visibility.

Main Responsibilities:

  • Lead the team that establishes, expands, and maintains DNA Scripts’ presence in the digital and print space.
  • Deliver an annual marketing and communications strategy including digital marketing, engaging with internal and external stakeholders as needed to ensure predictable outcomes with accurate measurements of performance.
  • Serve as a bridge between product managers, marketing managers, and other internal teams with external marketing channels to execute marketing programs within a fast-paced cross-functional environment.
  • Work with internal stakeholders and the marketing team to execute marketing activities including email, digital and social media campaigns and events.
  • Reactive and responsive, taking full responsibility to resolve issues and regain momentum.
  • Continuously update, improve, optimize (SEO) and analyze DNA Script’s website performance.
  • Regularly track and report on digital engagement metrics across outlets, programs, and messages.
  • Identify opportunities and channels for campaigns and events to reach the target audience.
  • Engage with KOLs to facilitate development of content, webinars, seminars, testimonials.

Preferred experience

Experience:

  • Minimum of Bachelor’s degree with 9+ years of progressive experience in digital marketing and marketing communications, with preference given to candidates experienced in scientific markets and genomics products.
  • 2-3 years of experience coaching, mentoring, and leading members of a marketing team.
  • In depth understanding of digital marketing fundamentals, tactical planning, and content development.
  • In depth understanding of media channels, life science publishers and genomics terminology.
  • Proficient user of creative software tools including Adobe creative suite and paid digital services such as Adwords, YouTube, Facebook, LinkedIn, and Twitter.
  • Expertise in web optimization and web analytics, marketing, communications, web design, and creating multi-channel user journeys to acquire, activate, and retain supporters.
  • Experience with creative design and copywriting preferred.
  • Demonstrated bias for action and results, but with a careful attention to detail.
  • Detail-oriented with effective time and project management skills.
  • Excellent written, presentation, communication and collaboration skills with experience presenting to diverse scientific and business audiences.

Recruitment process

  1. Phone interview with manager
  2. Day interview with manager; the team and HR
  3. Reference check
  4. Timing: 2 to 3 weeks
Apply now

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionately impatient people. We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”. We offer the opportunity of joining a dynamic, international, and highly skilled team in a pioneering startup. Our SYNTAX DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have a far-reaching impact across biological sciences.

The Role

The Inside Sales Representative manages the customer sales process for products, accounts and/or sales opportunities via phone and e-mail. Includes generating qualified sales leads, qualifying new opportunities, guiding customers to products that best meet their needs, coordinating with internal team to address customer questions/objections, providing budgetary pricing, and collaborating with the field sales team on closing the sales.

Responsibilities:

  • Demonstrates technical credibility to consult with customers on technology solutions.
  • Independently establishes and executes on strategies for obtaining new customers and maintains/grows existing customer accounts in order to meet and exceed revenue goals.
  • Helps specific sales team to meet sales targets, provide accurate forecasting, and in maintaining lead, opportunity, and customer information in the CRM database.
  • Activities include further qualifying in-bound marketing qualified leads, engaging with existing customers and qualified sales leads, guiding customers to the products that best meet needs, coordinating with internal team to address customer questions or objections, providing budgetary pricing, creating and submitting individualized quotes and closing the sales process through the point of order receipt.
  • Makes outbound contact to prospective customers to identify sales opportunities.
  • Takes an analytical approach towards executing optimal solutions for an issue or opportunity.
  • Has the ability to learn, change, and gain from each experience to become more effective in subsequent sales scenarios.
  • Works effectively in a team environment to drive and create revenue opportunities.

Preferred experience

  • Start-up mind-set.
  • Bachelor’s degree in Biology, Molecular Biology, Biochemistry or related field; or the equivalent knowledge and experience.
  • 2+ years of experience in a Life Science laboratory in one of the following fields (qPCR, NGS, genetic testing, synthetic biology), with or without prior sales experience.
  • Demonstrated ability to quickly grasp and master highly technical concepts and articulate them well to others
  • Exceptional listening, verbal and written communication skills. Ability to articulate well and think quick on your fee
  • Strong desire to win business and establish long term customer relationships.
  • Extensive knowledge of Molecular biology techniques.
  • Proficient with Microsoft Word, Excel and PowerPoint and CRM database required.
  • Fluent in English and French, additional languages a plus

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview with manager, cofounders, HR and the team
  3. References Check
  4. Timing: 2-3 weeks
Apply now

Opportunity and challenges

We are looking to assemble a team of best-in-class, innovative and passionate people. We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”. We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

DNA Script is actively searching for an accomplished Field Service Engineer to support our partners and customers in their use and application of DNA Script’s commercial product.
The individual will be responsible for leading complex technical inquiries in the field including troubleshooting and repairs, coordinating customer feedback and interactions, and representing user experiences within the company to aid development of next generation products.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.

The position will be US based, in the South San Francisco, California office.

Responsibilities:

  • Installs and optimizes hardware/software/network products and configurations at customer sites.
  • Diagnoses and resolves product performance problems.
  • Performs maintenance and repairs
  • Ensures customer satisfaction by advising customers on preventive maintenance and configurations, which may impact product performance.
  • Proactively responds to potential equipment issues to prevent unplanned interruption of customers’ business.
  • Delivers fully integrated solutions, which may include peripherals, communications, operating systems and applications software.
  • Trains other field engineers and customers in the company’s system products.
  • Provides user-oriented and service-related inputs to ongoing and new development projects.

Preferred experience

Experience:

  • Bachelors within the science field — e.g. biomedical engineering, analytical biochemistry, biotechnology or similar is highly preferred
  • 4+ years of experience in a similar position and/or experience as an end-user of analytical instrumentation
  • Ideal Candidate will have:
  • Experience or expertise with Laboratory Automation solutions (eg. pipetting robots, electronics and linear actuators) and systems involving reagents and consumables
  • Experience with troubleshooting and problem solving Customer service and solutions-oriented, with capability to precisely document issues, root cause analyses, troubleshooting experimentation and resolutions/repairs.
  • DNA Synthesis Experience, or Utilization of Synthetic Oligos in a biochemical application.
  • Excellent written and verbal communication skills
  • Ability to travel extensively including overnight travel as dictated by business needs

Miscellaneous

  • Remote Job based in the South West US, preferred in San Diego, CA. Requires 75% travel to corporate offices and client sites throughout the South West and other parts of North America.

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview at the office with manager, cofounders, HR and the team
  3. References check
  4. Timing: 2-3 weeks
Apply now

Opportunity and challenges

We are looking to assemble a team of best-in-class, innovative and passionate people. We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”. We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

DNA Script is actively searching for an accomplished Field Service Engineer to support our partners and customers in their use and application of DNA Script’s commercial product.
The individual will be responsible for leading complex technical inquiries in the field including troubleshooting and repairs, coordinating customer feedback and interactions, and representing user experiences within the company to aid development of next generation products.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.

The position will be US based, in the South San Francisco, California office.

Responsibilities:

  • Installs and optimizes hardware/software/network products and configurations at customer sites.
  • Diagnoses and resolves product performance problems.
  • Performs maintenance and repairs
  • Ensures customer satisfaction by advising customers on preventive maintenance and configurations, which may impact product performance.
  • Proactively responds to potential equipment issues to prevent unplanned interruption of customers’ business.
  • Delivers fully integrated solutions, which may include peripherals, communications, operating systems and applications software.
  • Trains other field engineers and customers in the company’s system products.
  • Provides user-oriented and service-related inputs to ongoing and new development projects.

Preferred experience

Experience:

  • Bachelors within the science field — e.g. biomedical engineering, analytical biochemistry, biotechnology or similar is highly preferred
  • 4+ years of experience in a similar position and/or experience as an end-user of analytical instrumentation

Ideal Candidate will have:

  • Experience or expertise with Laboratory Automation solutions (eg. pipetting robots, electronics and linear actuators) and systems involving reagents and consumables
  • Experience with troubleshooting and problem solving Customer service and solutions-oriented, with capability to precisely document issues, root cause analyses, troubleshooting experimentation and resolutions/repairs.
  • DNA Synthesis Experience, or Utilization of Synthetic Oligos in a biochemical application.
  • Excellent written and verbal communication skills
  • Ability to travel extensively including overnight travel as dictated by business needs

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview with the manager, cofounders, HR and the team
  3. References checks
  4. Timing: 2-3 weeks

Miscellaneous

Remote Job based in the Mid Atlantic US, preferred in MD/VA area. Requires 75% travel to corporate offices and client sites throughout the South East and other parts of North America.

Apply now

Sr. Product Manager – SYNTAX Instrument

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionately impatient people. We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write.” We offer the opportunity of joining a dynamic, international, and highly skilled team in a pioneering startup. Our DNA On Demand platform not only has the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.

The Role

We are seeking an experienced product manager to join our team and help lead the development and commercialization of instruments within the SYNTAX platform. This position will require working within a cross-functional product development team alongside members from commercial, R&D, project management, manufacturing, and other roles. The position will be responsible for developing, communicating, and owning business cases for instruments and instrument features, including customer requirements, financial assumptions, pricing, product fit, and integration with genomics workflows, from oligo sequence to downstream application.

The successful applicant will ideally have experience thriving in a dynamic and rapidly evolving organization, working proactively and independently across multiple job functions to execute on commercial priorities with limited resources, support, and high expectations.

Main Responsibilities:

  • Defines and updates business plans for SYNTAX instruments in alignment with the company’s objectives.
  • Manages SYNTAX applications landscape with analysis and understanding of customer needs and requirements, as well as current or emerging technologies, applications, and industry trends.
  • Manages the SYNTAX instrument portfolio, including product and financial performance, as well as forecasting and lifecycle management.
  • Represents the commercial organization and the needs of customers as part of the product development process and core team.
  • Serves as the commercial driver of product launch activities.
  • Collaborates with others across the marketing organization on product marketing for on-market products, including messaging, collateral, content, campaigns, and communications.
  • Supports sales, applications, regional marketing teams with training and collateral development.
  • Develops and fosters a DNA Script community, in partnership with others in the organization, as well as with distributors, customers, and broader scientific or lay audiences.

Preferred experience

Experience:

  • Minimum of Bachelor’s degree in life sciences or a related field, graduate degree (including PhD and/or MBA) preferred.
  • 5+ years in life sciences or related industry marketing experience, with preference given to candidates with strong experience in oligo synthesis and related research areas.
  • Life sciences or related industry product management and product marketing experience.
  • Experience with market research, financial analysis and modeling, strategic planning, product launch go-to-market planning, and lifecycle management.
  • Experience in cross-functional teams.
  • Experience with Jira SW for project management and coordination.
  • Effective time and project management.
  • Excellent written, presentation, communication and collaboration skills with experience presenting to diverse scientific and other audiences.
  • Travel up to 25%.

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview at the office with manager, HR, cofounders and the team
  3. References check
  4. Timing: 2-3 weeks
Apply now

The Role:

We are looking for a full-time trainee lawyer to join our legal team, and be based in our Kremlin-Bicêtre office.

The role will be a broad one, in close relationship with our General Counsel, and will range from contractual topics related to our operations, to reasearch with respect to regulation in the biotech field, or various other legal matters (incl. labor law, corporate law, etc.).

This is an exciting opportunity for someone wanting to have an in-house training in a favoured field, i.e. a fast paced growing biotech. If you are ready to make an impact at a mid stage life sciences company and looking for professional growth, you will thrive here at DNA Script.

Responsibilities:

  • Assist on the day to day corporate management (General assembly / board / stock-options allocations, etc.)
  • Assist in the creation of contractual models, and the creation of new ones.
  • Assist in the management of contract documentation flow, approvals, reporting and archiving consistent with internal processes.
  • Participate into the drafting, negociation, and follow up on exécution of wide variety of contracts of DNA Script.
  • Assist in researching and advising on financial/commercial/consumer laws which could apply to DNA Script directly or could otherwise impact its business.
  • More generally, DNA Script being a scale up, we also expect the trainee, as part of the legal team to be flexible and jump in on other topics and help other team members on other areas as the need may arise from time to time.

Preferred experience

Preferred Experience:

  • Trainee lawyer / élève avocat(e) or ending his / her Master (M2 studies) in Business Law, new technologies, commercial law or IP.
  • A LLM or other international experience and / or Master in Business school.
  • Excellent written and verbal communication skills.

Ideal Candidate will be:

  • Creative and practical thinker who can communicate information accurately and completely, while being concise and digestible for non-lawyers.
  • Team player standing ready to help colleagues.
  • Demonstrate interest for DNA / biotech related matter.
Apply now

The role

We are looking for an experienced HR Manager, US to manage a variety of HR projects for the US site. The HR Manager, US will plan, lead, direct, develop, and coordinate the policies, activities, and staff of the US HR department, ensuring legal compliance and implementation of the organization’s mission and talent strategy. The candidate will be in contact with external recruiters, lawyers, management team in the US, and the French HR team to coordinate the deployment of the HR strategy. The position reports to the Vice-President, Corporate Operations, based in France.

Responsibilities

Hiring and onboarding

  • Contribute to the definition of a global strategy to lead adhesion to and promotion of the company’s core values: Excellence, Transparency and Goodwill, on the South San Francisco site.
  • Contribute to the definition of a global strategy to identify and hire top performers and lead its execution on the South San Francisco site.
  • Contribute to the definition of a global strategy to integrate, incentivize and retain talents, in particular key employees, and lead its execution on the South San Francisco site.
  • Liaise with the broader US management team to understand the company’s goals and strategy related to staffing.
  • Collect and qualify needs for US-based positions with respect to budget and business requirements.
  • Manage end-to-end hiring process for US-based positions, including job posting, headhunter management, support of hiring managers during the interview process, contract drafting and onboarding.
  • Suggest process improvements and implement them in the most effective way.

Training, performance and retention

  • Liaise with the broader US management team and US employees to understand training needs.
  • Define and implement a talent development and retention strategy for US-based employees, in connection with the company’s global strategy.
  • Organize, implement and monitor mandatory trainings (security, quality, harassment, etc.).
  • Define and create internal training material.
  • Lead the performance review process for US-based employees.
  • Administration
  • Draft all relevant contractual documents, including offer letters, employment contracts and termination letters.
  • Oversee administration of compensation, benefits, time-off policies, visa requests, etc.
  • Lead exit interviews, disciplinary procedures, disputes, and investigations.
  • Ensure continued compliance with federal, state, and local employment laws and regulations, and recommended best practices.
  • Ensure compliance of HR processes for US-based employees with relevant data protection regulations (e.g. CCPA if/when relevant) and any quality requirements with which the company wishes to engage.
  • Define and implement budget and KPIs.
  • Prepare reports and presentations for management and/or company-wide meetings.

HR marketing and communication

  • Update and adapt HR internal and external communication tools (employee handbook, social networks, career website, etc.) to the US context.
  • Develop a common company culture in collaboration with the French HE team.
  • Organize events to promote company culture and wellness (e.g. seminars, dinners, etc.).
  • Benchmark cultural and managerial practices against best-in-class companies for continuous improvement.
  • Cross-functional projects
  • Administer occupational health and safety.
  • Conduct research and analysis of organizational trends including review of reports and metrics.

Preferred experience

Essential

  • Bachelor’s degree in Human Resources, Business Administration, or related field required; Master’s degree preferred.
  • At least five years of experience in human resource management required.
  • Thorough knowledge of employment-related laws and regulations, in particular in California.
  • Ability and willingness to get things done.
  • Ability and willingness to manage projects at operational level.
  • Strong analytical and problem-solving skills.
  • Excellent verbal and written communication skills.
  • Excellent organizational skills and attention to detail.
  • Excellent reporting skills.
  • Excellent time management skills with a proven ability to prioritize and meet deadlines; ability to efficiently mobilize external resources and coordinate projects.
  • Ability to work in a global organization.
  • Proficient with Microsoft Office Suite or related software.

Desirable

  • Experience in the biotech industry.
  • Start-up mindset.
  • Experience in a scale up environment.

Additional Information

  • Job located in South San Francisco
  • Start date: ASAP

Recruitment process

  • Phone interview with the hiring manager
  • Day interview with manager, cofounders, HR and the team
  • References check
  • Timing: 2-3 weeks
Apply now
Manufacturing Operations

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionate people. We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”. We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

DNA Script is actively searching for a Logistics Technician who will be primarily responsible for receiving and shipping under good laboratory practices. This role will include inventory follow up, execute products preparation to build the kits with full traceability and interact with Supply Chain teams to support customer demands.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.

The position will be US based, in the South San Francisco, California office.

Responsibilities:

  • Manage goods receiving, check conformity, records into ERP system (NetSuite / Oracle)
  • Maintain inventory for laboratory and manufacturing operations at South San Francisco site
  • Assemble and pack the kits and consumables
  • Ship the kits to customers for both domestic and international shipment
  • Manage express shipment companies in daily operations (shipments, follow-up …)
  • Work with supply chain team and our ERP (NetSuite) to optimize packaging and shipments, eliminating back orders
  • Maintain finished goods inventory, work in process and raw materials; recommend material orders as needed to maintain stocks for production
  • Participate in planning activities pertaining to kit production
  • Help in writing all QC procedures in coordination with Paris office QA team
  • Procure and receive materials to support kit production and shipping
  • Execute tasks under approved SOPs, document production using batch records and contribute to improving overall quality in operations
  • Contribute to development and execution of incoming inspection of received goods and stability tests
  • Work under the supervision of Laboratory manager

Preferred experience

Experience:

  • Bachelor degree in Logistics, or related field.
  • 3 – 5 years of relevant experience is preferred
  • Experience working in laboratory
  • Experience working under GLP (Good Laboratory Practices) and following good documentation and compliance practices
  • Experience with laboratory safety procedures and documentation
  • Detail oriented and meticulous attention to detail
  • Willingness to take/accept new responsibilities and able to work with minimal supervision.
  • Demonstrated ability to work in multidisciplinary teams

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview at the office with manager, HR, cofounders and the team
  3. References Check
  4. Timing: 2-3 weeks
Apply now

DNA Script renforce son équipe de production et recherche un Technicien(ne) Logistique, sous la responsabilité de la Direction Industrielle & Supply Chain.

Responsabilités

Gérer les stocks nécessaires à la production

  • Sorties et entrées du stock, commandes du matériel nécessaire, inventaires des matières premières et consommables, etc.
  • Assurer la réception et le suivi des stocks des matières premières, articles de conditionnement et consommables nécessaires à la production
  • Interagir avec les équipes Supply Chain en support de la production

Préparation des kits

  • Assurez la préparation et le conditionnement des kits dans le respect des protocoles internes, et saisir toutes les transactions dans l’ERP (NetSuite)
  • Assurer la traçabilité des « kits »
  • Exécuter le planning de production tel qu’établi par la Supply Chain
  • Garantir les volumes de production attendus et une qualité de production constante
  • Gestion documentaire dans le respect des normes réglementaires

Assurer la préparation des expéditions vers notre filiale et nos clients

  • Approvisionner les articles de conditionnement
  • Déclencher et suivre les expéditions (température ambiante et à -20°C)
  • Mettre à jour les stocks dans l’ERP

Participer à l’amélioration continue des méthodes de production

  • Proposer des améliorations des pratiques et des méthodes de production mises en place afin d’assurer la montée en cadence due à la commercialisation
  • Être acteur de l’amélioration continue de la qualité

Profil recherché

Expérience

  • Minimum 3 ans d’expérience sur une fonction similaire
  • Expérience de travail en environnement réglementé (production appareillage médical ou produits pharmaceutiques)
  • Expérience de travail avec un ERP (NetSuite / Oracle)
  • Respect des règles de sécurité et des référentiels internes de qualité et réglementaire
  • Bonne organisation et autonomie
  • Travail d’équipe
  • Organisé(e) et assidu(e)
  • Maîtrise du Français
  • Anglais technique

Déroulement des entretiens

  1. Entretien téléphonique avec le hiring manager
  2. Entretiens avec l’équipe, un cofondateur et les RH
  3. Prise de références
  4. Timing: 2 à 3 semaines
Apply now

Mission

DNA Script est à la recherche d’un responsable de production d’enzymes pour renforcer la production de ses enzymes propriétaires. Vous dirigerez la nouvelle équipe de production d’enzymes et serez en charge des activités de fermentation et de purification sous la supervision du directeur des opérations. Vous aurez la charge de gérer le processus de production de différentes enzymes à l’échelle pilote afin de garantir les volumes de production attendus et une qualité de production constante. Vous devrez collaborer avec d’autres équipes, notamment les équipes internes de R&D Enzymes et assurer le transfert de technologie avec des partenaires externes.

Responsabilités

  • Superviser les équipes USP et DSP
  • Maintenir une documentation détaillée de tous les processus de travail
  • Gérer les activités opérationnelles dans les zones de fermentation et de purification
  • Prendre des mesures correctives immédiates si nécessaire
  • Aider à développer des processus robustes et soutenir le transfert de processus vers des partenaires externes
  • Gérer la mise à l’échelle et la mise en œuvre des processus USP / DSP pour plusieurs enzymes et valider de nouveaux processus
  • Participer à la rédaction des instructions de travail (SOP, Formulaires, WI, Batch record) ainsi que de rapports pour le suivi interne et conformes aux exigences du système qualité mis en place
  • Reconnaître et résoudre les problèmes techniques et évaluer les options pour résoudre des problèmes complexes
  • Participer à la maintenance de routine et à la sécurité du laboratoire en suivant les procédures et les bonnes pratiques de laboratoire
  • Participer aux réunions de l’équipe de production et présenter de rapports techniques

Profil recherché

Qualifications and expériences

  • Détenir une maîtrise/un diplôme d’ingénieur ou un doctorat de préférence en biochimie, biotechnologie ou dans un domaine similaire
  • 8+ ans d’expérience dans la production de protéines
  • Connaissances théoriques approfondies et expérience pratique des techniques de chromatographie
  • Expérience industrielle en scale-up à l’échelle pilote/commerciale
  • Compétences démontrées en gestion et en leadership de l’équipe scientifique
  • Excellentes compétences en communication orale et écrite en anglais, un bon niveau de français est un plus
  • Proactif avec un excellent esprit d’équipe
  • Apprécier le travail de laboratoire dans un environnement dynamique et évolutif

Divers

  • Emploi situé au Kremlin-Bicêtre (région Parisienne, à 5 minutes de la porte d’Italie)
  • Date de début : Dès que possible
  • CDI

Déroulement des entretiens

  1. Entretien téléphonique avec le hiring manager
  2. Entretiens dans nos locaux avec le manager, l’équipe, les RH et co-fondateurs
  3. Prise de références
  4. Timing: 2 à 3 semaines
Apply now

Opportunity and challenges

We are looking to assemble a team of best-in-class, innovative and passionate people. We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”. We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

DNA Script is actively searching for a Manufacturing & Procurement Technician who will be primarily responsible for the preparation of kits under good laboratory practices. This role will include inventory follow up, execute products preparation to build the kits with full traceability and interact with R&D teams to support customer demands. In addition, she/he will be responsible for procurement of all necessary items for kits production.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.

The position will be US based, in the South San Francisco, California office.

Responsibilities:

  • Prepare buffers, solutions, and other kit components following approved protocols, including the use and safe handling of hazardous chemicals, data input and record keeping
  • Use approved analysis techniques to characterize and ensure quality of synthesis reagents and products
  • Work with supply chain team and our ERP (NetSuite) to optimize packaging and shipments, eliminating back orders
  • Maintain inventory for laboratory and manufacturing operations @ SSF site
  • Maintain finished goods inventory, work in process and raw materials; recommend material orders as needed to maintain stocks for production
  • Monitor, qualify, and maintain calibration of laboratory instrumentation used for manufacturing
  • Participate in planning activities pertaining to kit production
  • Help in writing all QC procedures in coordination with Paris office QA team
  • Perform reagent manufacturing, logistics planning and other tasks as necessary in a laboratory environment
  • Assist in assembly and packaging of reagents and consumables for both domestic and international shipment
  • Procure and receive materials to support kit production and shipping
  • Execute tasks under approved SOPs, document production using batch records and contribute to improving overall quality in operations
  • Contribute to development and execution of incoming inspection of received goods and stability tests
  • Work under the supervision of Manufacturing Operations management

Experience:

  • Bachelors degree in Biology, Biochemistry, Chemistry or related field.
  • 1-3 years of relevant experience is preferred
  • Experience working in laboratory
  • Experience working under GLP (Good Laboratory Practices) and following good documentation and compliance practices
  • Experience with laboratory safety procedures and documentation
  • Detail oriented and meticulous attention to detail
  • Willingness to take/accept new responsibilities and able to work with minimal supervision.
  • Demonstrated ability to work in multidisciplinary teams

Miscellaneous

  • Job located in South San Francisco
  • Start date: Q3 2021

Recruitment process

  • Phone interview with the hiring manager
  • Day interview with manager, cofounders, HR and the team
  • References Check
  • Timing: 2-3 weeks
Apply now
Product Development

The role

We are looking to assemble a team of best-in-class, innovative and passionate people. We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”. We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.
DNA Script is actively searching for a Senior Back-end Software Engineer to implement the web-based Lab Information Management System.
This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.

Responsibilities

  • Design and develop web applications and APIs supporting our business and product needs.
  • Work with product management and marketing to capture and define software requirements and influence overall product implementation direction.
  • Collaborate with UX design personnel, front-end engineers, internal and external customers to understand their needs, objects, and use cases to design and implement more functional and cohesive code to enhance the user experience.
  • Strong technical leadership skills with the ability to solve complex problems
  • Constant quality improvement of code and infrastructure

Preferred experience

Qualifications and experience

Essential

  • A Bachelor’s Degree, or a Master’s Degree in software engineering or related field.
  • 5+ years of software development in an e-commerce or SaaS environment using Java.
  • Prior experience developing and launching cloud-based production SaaS on AWS.
  • Experience developing server-based application and micro-services using Java frameworks like Spring Boot, Play, etc.
  • Experience developing against both SQL and No-SQL with strong database knowledge and design.
  • Experience with Atlassian applications including BitBucket, JIRA, Confluence, and other 3rd party development tools and utilities.
  • Self-motivated, self-starting, an attention to detail and a great team player.
  • The highest level of personal honesty, integrity and commitment; unquestionably walks the talk so others want to follow.
  • Strong communication skills.
  • Proficient in English

Desirable

  • Familiarity with enterprise NGS cloud-based systems.
  • Experience with message brokers such as MQTT or Kafka.
  • Experience integrating with Oracle’s ERP or NetSuite via web services API or equivalent.
  • Experience developing micro-services using Python with web service frameworks like Flask
  • Background in biological sciences, DNA applications, either from education or work experience.

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview with manager, cofounders, HR and the rest of the team
  3. References Check
  4. Timing: 2-3 weeks
Apply now

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionately impatient people. We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write.” We offer the opportunity of joining a dynamic, international, and highly skilled team in a pioneering startup. Our DNA On Demand platform not only has the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

The candidate selected for this role will lead a new department within DNA Script’s Product Development organization responsible for all aspects of reagent, kit and consumable development from technology transfer from the R&D organization through to design transfer to Operations.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.

The position will be based in the Paris Headquarters.

Responsibilities:

  • Provide strategic leadership and technical direction in defining and achieving reagent, consumable, and kit development objectives
  • Ensure that plans are in place and execute accordingly to clearly establish performance specifications of incoming and outgoing material, establish analytical and functional tests required for qualifying raw material and finished goods
  • Drive reagent development and improvements to include buffer formulations, enzyme clone optimization, and nucleotide and other raw material refinement
  • Create and implement processes for formulation optimization, guardbanding, and stability improvements including initial characterization, verification and validation for each element
  • Translate feasibility-ready formulation instructions into scaled-up and formalized work instructions ready for handoff to Manufacturing Operations
  • Define and/or design reagent storage, custom consumables, labeling and packaging design & materials
  • Define and execute reagent, consumable, and kit verification and validation criteria and protocols
  • Develop analytical and functional acceptance criteria and QC metrics for all related DNA Script Product lines
  • Specify raw materials acceptance criteria and specifications
  • Conceive, develop, and validate new QC methods and specifications
  • Lead efforts with Manufacturing Operations to ensure specs are finalized, BOMs, SOPs/Work Instructions, QC protocols are finalized and ready for process validation.
  • Develop content for Instructions for Use and/or User Guides and transfer to Technical Support
  • Partner with Manufacturing on Alpha Builds for testing and Early Access programs
  • Partner with Product Marketing and Sales to provide data as needed to ensure successful product launch
  • Hire and mentor a successful development team

Experience:

  • Masters or Ph.D. in Molecular Biology, Biotechnology, Genetics or equivalent
  • At least 10 years of experience in developing life science reagents for the US and other key markets, with at least 5 years of leadership responsibility
  • Demonstrated success in developing and optimizing molecular biology reagent kits, custom consumables, and/or assays
  • In depth knowledge of molecular and analytical techniques such as DNA synthesis, NGS, qPCR, nucleic acid characterization, capillary electrophoresis, HPLC, and spectroscopic techniques
  • Excellent organizational skills and attention to detail
  • Excellent verbal and written communication skills
  • Strong supervisory skills and a thoughtful and effective approach to department leadership

Ideal Candidate will have:

  • Excellent project management skills with a proven ability to meet deadlines and drive to product launch
  • Strong analytical and problem-solving skills
  • Ability to prioritize tasks and to delegate them when appropriate
  • Ability to function well in a high-paced and at times stressful environment
  • Proficient with statistical analysis software

Miscellaneous

  • Job located in Paris
  • Frequent travel between global DNA Script sites
  • Start date: ASAP

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview with the manager, cofounders, HR and the rest of the team
  3. References check
  4. Timing: 2-3 weeks
Apply now

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionate people. We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”. We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.

The position will be US based, in the South San Francisco, California office.

Responsibilities:

  • Provide hardware technical support for increasingly mature implementations, from prototypes through production
  • Interface with and collaborate with internal and external development partners, accelerating product development
  • Operate and optimize prototype hardware systems, perform software and hardware troubleshooting
  • Develop, document, and execute initial on-market support materials, strategies, SOPs, and Service Manuals
  • Install, test, and support systems at customer sites
  • Train field service personnel and develop training materials
  • Contribute to risk assessments, design reviews and participate in CAPA/SCAR process
  • Utilizing issue/complaint log, create reliability/failure summary report that identifies frequency of issues by area of impact to the instrument and/or customer workflow (eg pipetting, software errors, results).
  • Assist with design transfer to manufacturing, process validation, and manufacturing documentation, as needed
  • Assist with / perform system verification and validation tests as needed
  • Track open technical issues, manage status of support issues, and escalate as required according to procedures
  • Work with instrument and part vendor(s) for failure investigations and root cause determination. Facilitate return of material to vendor for repair/rework.
  • Collaborate with Marketing team to optimize user acceptance testing and identify new applications for product

Experience:

  • A Bachelor’s degree, or higher, in an Engineering discipline or related field.
  • 2-5 years of relevant industry experience in field or internal support of life science instrumentation or diagnostic devices.
  • Experience with troubleshooting and problem solving Customer service and solutions-oriented, with capability to precisely document issues, root cause analyses, troubleshooting experimentation and resolutions/repairs.
  • Excellent written and verbal communication skills in technical writing and ability to document and communicate problems and solutions

Ideal Candidate will have:

  • Background in biological sciences, DNA applications, either from education or work experience
  • The ability to represent the Company in front of customers, collaborators, industry peers and scientists
  • Experience or expertise with Laboratory Automation solutions (eg. pipetting robots, electronics and linear actuators) and systems involving reagents and consumables
  • Laboratory experience involving PCR/qPCR is highly desired
  • DNA Synthesis Experience, or Utilization of Synthetic Oligos in a biochemical application
  • Ability to travel occasionally including overnight travel as dictated by business needs

Recruitment process

  1. Phone Interview with the hiring manager
  2. Day interview with manager, HR, cofounders and the rest of the team
  3. References Check
  4. Timing: 2-3 weeks
Apply now

We are looking to assemble a team of best-in-class, innovative and passionate people. We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”. We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

DNA Script is actively searching for a motivated and efficient Engineering Technician who will be focused on enabling and testing our DNA synthesis technology and the development of DNA Script’s commercial product. This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.

The position will be US based, in the South San Francisco, California office.

Responsibilities

  • Work closely with team members to improve quality and performance of mechatronic and automation platforms
  • Perform mechanical, electrical, and fluidic tests on prototypes. Document results clearly, using approved templates
  • Operate, maintain, and perform advanced service on prototypes. Address issues in a timely manner.
  • Troubleshoot, repair and requalify prototypes and associated test equipment .
  • Assemble components, subsystems, and systems for testing.
  • Perform operational test and fault isolation on systems and equipment.
  • Assist in determining methods or actions to remedy malfunctions.
  • Assist in the design, construction, test and check-out of test equipment.
  • Use manufacturing, test, development, and/or diagnostic equipment, including, but not limited to, test programs, oscilloscopes, signal generators and specialized test apparatus.
  • Work closely with development engineers to conduct engineering tests, collect performance data, and/or assist in research work.
  • Maintain a clean work environment including instruments and equipment and workspace

Preferred experience

  • Bachelor’s degree in engineering discipline with 1 year of experience

Ideal Candidate will have:

  • Experience with instruments including electromechanical systems, especially linear actuators and fluidics.
  • Extensive experience diagnosing and correcting problems with instruments or equipment.
  • Experience and aptitude with testing light mechanical systems.
  • Familiarity with electrical circuits and power supplies.
  • Ability to follow documented procedures as well as keep organized lab notebook
  • Experience using mechanical tools to assemble and disassemble instrument components, modules, and full systems
  • Experience working on analytical instruments combining mechanisms, electronics, automation, and fluidics.
  • Hands-on experience with breadboard/prototype builds and automation/fluidics optimization.
  • Ability to troubleshoot electronic circuits.
  • Experience in reliability or life testing. Experience developing fixtures and instrumentation for assembly and testing.

Recruitment process

  1. Phone interview with the manager
  2. Day interview at the office with the manager, cofounders, HR and the team
  3. References check
  4. Timing: around 2-3 weeks

Miscellaneous

  • Job located in South San Francisco
  • Start date: Q2 2021
Apply now

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionate people. We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”. We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our DNA Synthesis platform will not only have the potential to change the way the world makes and uses synthetic DNA but will also accelerate the rate of discovery by delivering upon the promise of same-day results.

DNA Script is looking for an experienced Product Development Engineer to join our team, in a role that is focused on improving and expanding the capabilities of the company’s core synthesis platform. The candidate will be responsible for managing and improving the platform’s design documentation and ensuring product requirements clearly trace through to specifications and verification & validation protocols.

The candidate is expected to lead requirement generation, development of acceptance criteria and verification test cases, risk analysis, generation of specifications and participate in efforts to design improvements to the system. Additionally, the candidate will work collaboratively with the R&D team in Paris, engineering partners and software development.

The candidate will join a global team bringing together scientists from various fields of expertise. We are looking for a person who is rigorous, well organized and detail-oriented. Pro-active, the candidate should be a problem-solver and should have a strong ability to think “out of the box”, as well as willingness to suggest and to prove out new ideas.

The position will be based in the South San Francisco, California office.

Responsibilities:

  • Work closely with program management, field support, software and hardware teams to understand requirements, contribute to product improvements and new design activities, and develop associated verification and validation test criteria and procedures
  • Maintain traceability for on-market products between test reports and requirements, specifications, failure modes analysis, and CAPAs, throughout design controls.
  • Write and maintain design history file documentation
  • Write test protocols, conduct feasibility, verification, and validation testing, and record results in a clear, concise, and compliant manner.
  • Lead & perform efforts involving system robustness & stability. Conduct root cause analysis investigations; identify failure modes and resolutions.
  • Conduct periodic risk management reviews, updating design, process and use FMEAs.
  • Ensure all aspects of product testing and execution are performed within pre-specified program plans (including documentation such as protocols, reports, statistical analysis, deviations, root cause investigations).
  • Ensure that the product meets performance requirements, intended use, and user needs by
    conducting engineering tests, inspections, stability tests, and usability tests to evaluate individual components, subsystems, or the overall design.
  • Establish and maintain schedules to meet critical milestones.
  • Work with 3rd party vendors and cross-functionally to advance product development and testing.
  • Conduct failure investigations/root cause analysis for issues identified by field support and summarize evaluations and results through written or oral presentations.
  • Work cross-functionally to receive, prioritize, and implement design changes to improve quality and performance of DNA Script’s products in response to customer complaints and feedback

Preferred experience

  • BS or higher in engineering, chemistry, biochemistry, or related field
  • Minimum of 5 years’ experience working in continuing engineering or new product development involving biotechnology instrumentation, operating under design controls (21 CFR 820.30)
  • Experience creating and managing product requirement documentation & trace matrix
  • Experience creating design and product specifications
  • Experience troubleshooting/developing liquid handling automation systems, mechanical and electrical systems
  • Strong documentation skills and ability to effectively communicate verbally and in writing, utilizing Word, PowerPoint and Excel

Ideal Candidate will have:

  • Ability to organize and manage design documentation, respond to changes, and prioritize effectively
  • Strong analytical mindset, detail oriented, and adept at communicating ideas, concepts, and presenting data
  • Ability to solve complex problems and troubleshoot dynamic systems
  • Versatile and adaptable to new methods, technologies and approaches
  • Past experience developing systems for NGS / PCR applications is a plus
  • Excellent communications skills
  • Proactive, solutions-focused

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview with manager, cofounders, HR and the rest of the team
  3. References check
  4. Timing: 2-3 weeks
Apply now

The Role

We are looking to assemble a team of best-in-class, innovative and passionate people.  We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”.  We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

DNA Script is actively searching for a Senior Front-end Software Engineer to implement the web-based Lab Information Management System.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences. 

Responsibilities:

  • Design and develop e-commerce application supporting our business and product needs.
  • Work with product management and marketing to capture and define software requirements and influence overall product implementation direction.
  • Work closely with UX design personnel, clients and potential customers to understand their needs, objectives, and use cases, and develop applications meeting these specifications.
  • Strong technical leadership skills  with the ability to solve complex problems.
  • Constant quality improvement of code and infrastructure.

Requirements:

  • A Bachelor’s Degree, or a Master’s Degree in software engineering or related field.
  • 5+ years of software development in an e-commerce environment with various web-based applications, web store, inventory, order management, analytical reports, etc.
  • Prior experience developing and launching web-based SaaS on AWS and/or stand-alone software package.
  • Experience developing web applications using TypeScript, ReactJS, Apollo, and GraphQL (or JSON) API.
  • Experience integrating with third party solutions via web services API.
  • Experience with Atlassian applications including BitBucket, Jira, Confluence, and other 3rd party development tools and utilities.
  • Self-motivated, self-starting, an attention to detail and a great team player.
  • The highest level of personal honesty, integrity and commitment; unquestionably walks the talk so others want to follow.
  • Strong communication skills.

Ideal Candidate will have:

  • Familiarity with enterprise NGS cloud-based systems, ideally Illumina / Design Studio
  • Background in biological sciences, DNA applications, either from education or work experience.

Miscellaneous

  • Job located in Paris, France
  • Start date: ASAP 
Apply now
Regulatory and Quality

The role

We are looking for a Quality Assurance Engineer for providing support to maintain DNA Script Quality Management System. The Quality Assurance Engineer will help and manage several activities in the QA department, in compliance with ISO 13485 & 21 CFR 820. The ideal candidate must be autonomous, with good leadership skills, Quality mindset with strong influencing skills, with the ability to work independently, handle multiple tasks in parallel, and communicate effectively.

Responsibilities

  • Collaborate cross-functionally to review and approve Quality documentation for all departments (Manufacturing, Product Development, R&D, …): SOPs, Work Instructions, Forms, …,
  • Manage Internal Audits activities: define audit program for the year, send audit notification, redact audit reports and follow-up the corrective actions,
  • Manage Quality Supplier activities: Supplier approvals and re-evaluation, Audits planning and realization, Quality Agreements,
  • Lead training records implementation and management in collaboration with the HR department,
  • Participate in the implementation of an eQMS software solution for DNA Script,
  • Participate in the management of Quality Operational events (Event, Nonconformance, Document control, Customer Complaint, CAPA, Change Control, …),
  • Participate in the review and approval processes of Manufacturing Operations records (Batch Records, Qualification reports, Validation reports).

Qualifications and experience

Essential

  • Master’s Degree in Quality, Biotechnology sciences, Pharmacy or equivalent.
  • At least 3 years of experience in Quality Assurance
  • Experience of working in a regulatory environment (ISO 9001/13485, 21CFR Part820 or BPF/GMP),
  • Experience in the biotech/pharma industry,
  • Autonomy, rigor, and proactivity,
  • Good written and verbal communication skills in French and in English.

Desirable

  • Auditor certification,
  • First experience in eQMS implementation/management,
  • First experience in Quality Supplier management,
  • Awareness of risk management,
  • Start-up mindset.

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview at the office with manager, cofounders, HR and the rest of team
  3. References Check
  4. Timing: 2-3 weeks
Apply now

Quality Control Engineer for enzymatic DNA synthesis reagent QC

The Role

Within DNA Script, the Synthesis Platform Team is in charge of synthesizing oligonucleotides for various molecular biology applications, as well as validating new reagents and performing reagent QC for manufacturing.

As part of the company expansion moving towards commercialization, reagent manufacturing is scaling-up and therefore reagent QC is becoming a full-time activity which needs to be externalized out of R&D, in a dedicated QC team with a structured quality management system. This transition is planned for beginning of 2022, the QC team being currently staffed.

Therefore, DNA Script is looking for a Quality Control Engineer for enzymatic DNA synthesis reagents.
The candidate will be responsible for ensuring that the products meet company requirements, by running QC tests mainly performing enzymatic synthesis on a liquid handler, analyzing and documenting the results, for all the reagents involved in enzymatic DNA synthesis (such as buffers, enzymes, nucleotides).

He/she will be collaborating mainly with the manufacturing teams, will be directly involved in the reporting of DNA Script product performances and contribute to their improvement. The position will require a lot of transversal and interdisciplinary communication mostly with the manufacturing team in France and US, the R&D synthesis team and the product development team.

Responsibilities

Your missions will be:

  • Perform all synthesis required for the Quality Control of all the batches of reagents, produced both in house and by external partners
  • Run those synthesis, based on appropriate protocols, on automated devices (liquid handlers), and thus be responsible for their maintenance and good performances
  • Analyze the results from capillary gel electrophoresis
  • Ensure compliance with safety and quality standards compatible with ISO 13485
  • Communicate the results to the Manufacturing team in order to release the reagent batches
  • For all unqualified reagents, follow-up with troubleshooting to determine the root cause and propose some remediation in a continuous improvement process
  • Manage stability studies of commercialized products
  • Work within the QMS team to help develop and maintain all required documentation
  • Manage the transfer of new synthesis protocols from the R&D validation system to the manufacturing scale
  • Engage in good laboratory/documentation practices, write Standard Operating Procedures (SOPs) and enforce their correct use.
  • Regularly present and report across all levels of the company.
  • Actively contribute to critical company milestones, with a willingness to work outside immediate area of expertise when required.

Qualification and experience

Essential

  • Master or Engineering degree in the field of molecular biology, biotechnology or quality
  • 1 to 2 years of experience as a Quality Control engineer or similar role
  • Understanding of manufacturing processes and quality/safety regulations (ISO 13485, BPL/GLP BPF/GMP or 21 CFR Part 820)
  • Willingness to work on liquid handlers, such as Tecan Evo, Hamilton Vantage
  • Down-to-earth mindset focused on finding simple solutions to complex problems.
  • Excellent organizational, analytical, and systematic troubleshooting skills.
  • Rigorous with a high attention to details.
  • Ability to work as part of a multidisciplinary team. Excellent communication and interpersonal skills.
  • Fluent in English
  • Highly motivated and proactive

Desirable

  • Experience in using liquid handling systems
  • Experience in nucleic acid synthesis
  • Experience in process optimization

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview at the office with manager, HR, cofounders and the team
  3. References check
  4. Timing: 2-3 weeks

Apply now

We are looking to assemble a team of best-in-class, innovative and passionate people. We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”. We offer the opportunity of joining a dynamic, international, and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

DNA Script is actively searching for a Quality and Regulatory Affair Director who will report directly to the CEO and be responsible of the creation and the management of all activities related to quality and regulatory. You will define procedures, advise operational departments, and guarantee the regulatory and quality compliance of products at each stage of their development, from concept to delivery.
In this context, you work closely with the various departments of the company (R&D, Product Development, Manufacturing, Marketing, Sales, Management) and the service providers.

Responsibilities

Strategy and build-up of activity

  • Build-up the Regulatory and Quality team and activities;
  • Create and maintain quality procedures, documentation and processes for the Company to operate at gold standard from industry stand-point;
  • Lead and be responsible for product certification in different regulatory frame-work and regions, in-line with Company strategy and objectives;
  • Lead the team in place (one engineer) to complete projects according to established timelines and needs, and develop the team in France and in the US;
  • Have a comprehensive knowledge of the product and its life cycle to analyze product characteristics and to review processes, objectives and constraints within each department;
  • Identify and analyze the regulatory framework and the modalities of introduction to the European and US markets for the product. Study the ISO 9001 and ISO 13485 certifications applicable in the company, as well as the internal quality objectives required by the Management team;
  • Define, propose and put in place the Regulatory and Quality strategy to the Management team for current and new product projects, by developing several iterations taking into account the risks and trends.

Quality

  • Define and implement the QMS system and software;
  • Create quality control tools and develop procedures;
  • Provide guidance and train each department to the quality rules and procedures;
  • Analyze performance indicators and manage incidents;
  • Manage audits and relations with certifying organisms;
  • Be responsible for identifying impacts of international regulations, standards and guidance to our Quality Management System.

Regulatory Affairs

  • Propose and lead a strategy regarding regulatory frame work, Company and product certification;
  • Provide guidance and training to explain the objectives of the regulatory provisions and define the procedures within the departments;
  • Control the respect of protocols;
  • Collect from the departments the information and technical documentation necessary for the preparation of registration, authorization or declaration files, as well as for CE marking. Lead preparatory meetings;
  • Lead and be responsible for all the certification process, relation with certification bodies and fillings;
  • Ensure that authorizations are obtained within the regulatory deadlines and those required by the sales objectives;
  • Control compliance (finished product, documentation, communication). Authorize the launching of batches;
  • Carry out studies and manage audits with service providers.

Qualifications and experience

Essential

  • Masters’ Degree in Medical/Biotech Engineering, Pharmacy or equivalent,
  • At least 8 years of experience in Regulatory Affairs and Quality Assurance environment, preferably with background in Biological Sciences,
  • Experience in the build-up of a Regulatory and Quality department,
  • Demonstrated management or supervisory experience with strong interpersonal and influencing skills,
  • Experience in ISO certifications (ISO 13485, ISO 9001, etc.) and CE marking,
  • Experience in medical device or Life science tool,
  • Excellent written and oral communication skills with a strong emphasis on organizational capabilities and external communications,
  • Demonstrated flexibility and adaptability in carrying out various assignments in a concrete way,
  • Operational and concrete problem-solving mindset,
  • Excellent written and verbal communication skills,
  • Strong organization and analysis/problem skills,
  • Strong attention to detail/quality focus,
  • Familiarity with Quality concepts and practices,
  • An in-depth knowledge of European and International regulations,
  • Fluent in English.

Desirable

  • Start-up mind-set is strongly preferred,
  • Understanding of the product introduction,
  • Experience in GMP.

Recruitment process

  • Phone interview with manager
  • Day interview with manager, cofounders, HR and the team
  • References check
  • Timing: around 2-3 weeks

You can also apply directly here.

Apply now
Research & Development

The role

DNA Script is looking for a talented individual to join the chemistry R&D team as Research Scientist – Nucleoside and Nucleotide Chemistry. The candidate will be responsible for synthesizing multiple types of modified nucleosides/nucleotides, one of the key reagents in DNA Script’s EDS technology, as well as participating in R&D projects to improve performance of enzymatic DNA synthesis technology. The position will report to the Modified Nucleotide Team Leader.

Responsibilities

  • Conduct synthesis and purification of modified nucleosides and nucleotide through various chromatography (flash chromatography, ion exchange chromatography, reverse phase chromatography) methods and instrumentation
  • Conduct analysis of modified nucleosides and nucleotides utilizing state-of-art analytical instruments, such as 1H/13C/31P NMR, HPLC and LC-MS
  • Record detailed procedures and results in lab notebook and write technical documents, such as work instruction (WI), standard operating procedures (SOP)
  • Prioritize and manage own work schedule to timely meet project milestones and deadlines
  • Train and mentor junior team member
  • Participate to the order and inventory of chemicals to maintain common stock in the chemistry laboratory
  • Perform maintenance of certain equipment of the laboratory
  • Perform other laboratory tasks assigned by Team Leader and Director of Chemistry
  • Participate in chemistry R&D team meeting and present weekly technical report
  • Maintain highest laboratory safety practice and keep the lab organized and tidy

Preferred experience

Qualifications and experience

  • Holds a PhD degree or Master degree in Organic Chemistry, Medicinal Chemistry or similar field with at least two years of industry experience
  • Expertise in multi-step organic synthesis and purification with hands-on experience in nucleoside, nucleotide chemistry
  • Expertise in various analytical and purification methods and instrumentation: pH meter, UV-Vis spectrometer, NMR, analytical and preparative HPLC, LCMS, thin-layer chromatography, flash column chromatography, ion exchange chromatography
  • Excellent written, organizational, and documentation skills
  • Excellent communication and interpersonal skills, efficient interaction with internal and cross functional team members
  • Ability to work independently and as part of a large multi-disciplinary team
  • Fluent English speaker

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview with manager, cofounders, HR and the rest of the team
  3. References Check
  4. Timing: 2-3 weeks
Apply now

The role

We are looking to assemble a team of best-in-class, innovative and passionate people. We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”. We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

DNA Script is actively searching for a Junior Bioinformatics Scientist to provide bioinformatic support to a number of our teams.

The ideal candidate should be enthusiastic and passionate about bioinformatics and related technologies. We are looking for a team player, who can rapidly adapt to challenges, and interact with different teams as new projects arise. This position would be an excellent match for someone who is comfortable working with both biologists and developers to translate biological data into actionable insights.

We have many different teams within DNA Script who have bioinformatic requirements, and this role will include assisting in both the rapid turnaround of biological questions into insight, as well as running and maintaining already established pipelines and tools. Thus, the ability to juggle multiple projects, both short-term and long-term, is crucial.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.

Responsibilities

  • Data Analysis of next generation sequencing (NGS) data
  • Data interpretation and visualisation
  • Developing and maintaining robust bioinformatic pipelines
  • Provide bioinformatic support to scientists working on a range of different projects
  • Report writing and taking part in team meetings and code review

Qualifications and experience

Essential

  • Either a MSc degree in bioinformatics with at least 2 years’ experience of working in a related field
  • Or a PhD in a related field (bioinformatics, computational biology)
  • Direct experience working with NGS data
  • Knowledge and experience developing and maintaining bioinformatics tools in Python
  • You will need to demonstrate a good level of expertise in Python and be experienced in the use common bioinformatic python-related technologies (pysam, pandas, conda, biopython)
  • Comfortable working to a high standard both independently and as part of a team
  • A strong background in using best-in-class tools and approaches to addressing bioinformatic problems (DNA-Seq, RNA-Seq)
  • Curious and analytical, with a proven ability to learn quickly
  • Proficient in English and a basic level of French

Desirable

  • Data visualisation in R (ggplot, tidyverse)
  • Experience in using workflow languages (snakemate, nextflow) to run pipelines
  • Experience working in a cloud environment (e.g. AWS)
  • Experience developing interactive tools using technologies such as Shiny
  • Machine learning / Statistics
  • Competence in working on a Linux command line
  • Experience with Docker/Singularity is a plus

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview with manager, cofounders, HR and the rest of the team
  3. References Check
  4. Timing: 2-3 weeks
Apply now

The role

We are looking for an analytical development engineer in the Analytics Team. His main mission will be to:

  • Conduct analytical development projects using UPLC/UV, UPLC/MS (SQ, Q-Tof), capillary electrophoresis (Agilent and Waters equipment) ensuring the reliability of the results by progressive validation of the methods,
  • Manage analysis of oligonucleotides samples and the interpretation of the data by collecting results from different analytical techniques in collaboration with R&D teams,
  • Take part to the standardization of lab practices (work instructions, reports, maintenance/ qualification program of the instruments)

The position reports to the Analytical Team Manager, based in France.

Responsibilities

  • Develop, improve new and existing analytical methods for sample preparation (automation/ liquid handling robot, SPE…), characterization and quantification of product/ impurities by UPLC/MS (low or high resolution), …
  • Ensure the progressive validation of the methods including the methods transfer in collaboration with the QC team,
  • Take part to the routine analyses program in medium and high throughput to support the R&D projects (oligonucleotides and key reagents as nucleotides and enzymes),
  • Interpret, validate the analytical results using a LIMS,
  • Ensure maintenance and verification of the instruments; enforce their performance by standardizing their use (work Instructions; logbooks; system suitability tests),
  • Write analytical development protocols and reports,
  • Ensure communication with other teams,
  • Contribute to the implementation of new techniques or collaborations,
  • Participate in the organization of the analytical laboratory

Preferred experience

Qualifications and experience

Essential

  • Minimum Master of Science or equivalent Engineering degree: chemical engineer, biochemist or related, preferably in Analytical chemistry, bio-analyzes,
  • At least 2-5 years of experience in analytical development using LC/MS on biomolecules,
  • Proficiency in chromatography (UHPLC), mass spectrometry and associated software
  • Excellent communication and interpersonal skills,
  • Ability to work independently and within a large multidisciplinary team,
  • Dynamic with a positive attitude willing to commit to a high level,
  • Good written and verbal communication skills in French and in English

Desirable

  • Experience in the biotech/pharma industry,
  • Start-up mindset.

Recruitment process

  1. Phohe interview with the hiring manager
  2. Day interview at the office with the manager, cofounders, HR and the rest of the team
  3. References Check
  4. Timing: 2-3 weeks
Apply now

The role

DNA Script is looking for a R&D Fermentation Scientist to strengthen the development and the production process of its proprietary enzymes. You will join the enzyme process team composed of 7 scientists and be in charge of the fermentation activity under the supervision of the enzyme process group leader.

Your mission will be to optimize bacterial fermentation processes for different recombinant enzymes. You will work together with the downstream processing team to maximize enzyme yields and reduce cost of goods.

You will also collaborate with other teams, especially enzyme engineering team, to improve DNA Script technology and enzyme manufacturing team to support process transfer to larger scale.

Responsibilities:

  • Manage USP operational activities and USP team
  • Define strategy for the development and optimization of the USP process for multiple enzymes
  • Develop robust upstream process and support process transfer internally and to external partners
  • Identify and implement new processes/instrumentation for continuous improvement of yield and throughput
  • Evaluate and maintain fermentation data and analysis in databases.
  • Conduct or coordinate experiments with a high level of excellence to ensure precise and accurate data.
  • Recognize and resolve technical problems and evaluate options for complex experimental problems
  • Support generation of WIs, SOPs, batch records and reports for internal tracking, technology transfer and development processes.
  • Prepare and communicate experimental outcomes in reports and presentations to technical audiences
  • Participate in routine maintenance and lab safety by following laboratory procedures and good laboratory practices

Qualifications and experience

Essential

  • Holds a Master or PhD degree in the field of Biological Process Engineering, Chemical engineering, Biotechnology or similar.
  • Has +5 years of hands-on experience in protein production.
  • Extensive theoretical knowledge and hands-on experience with microbial bioprocess development
  • Familiarity with protein purification
  • Excellent oral and written communication skills in English, good level of French
  • Proactive with excellent team spirit
  • Appreciate lab work in a dynamic and evolving environment

Desirable

  • Experience with different over-expression systems
  • Experience with strain engineering

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview with manager, cofounders, Hr and the rest of the team
  3. References check
  4. Timing: 2-3 weeks
Apply now

The role

DNA Script is looking for a Research Assistant to strengthen the development of its proprietary enzymes for EDS technology. You will join the enzyme engineering team composed of 10 team members and be part of an exciting oligonucleotide synthesis project.
Your mission will be to participate to the evolution of proprietary enzymes and develop improved variants for a specific project. You will work together with an Enzyme Engineering Scientist to generate and screen mutant libraries at a primary stage.
We’re looking for a highly motivated, well-organized team-player to join the team.

Responsibilities:

  • Help in preparing enzyme mutant libraries using PCR and cloning, plasmid preparation, transformation in E. coli
  • Conduct enzyme mutant library expression in E. coli and purification in plate format
  • Determine activity and stability of enzyme mutants in plate format using various assays
  • Analyze Sanger sequencing data of enzyme mutants
  • Characterize enzyme purity by SDS gel electrophoresis
  • Conduct experiments with a high level of excellence to ensure precise and accurate data.
  • Analyze, report and archive experimental data in spread sheet, documents, slides
  • Prepare and communicate experimental outcomes in reports and presentations to the team
  • Help in lab management, preparing buffers, ordering of consumables, record keeping

Qualifications

Essentials:

  • Bachelors’ or Master’ Degree in Biology, Biochemistry, Chemistry or similar field
  • Familiarity with protein handling and purification
  • Familiarity with protein assays (activity, stability, binding)
  • Strong record keeping skills
  • Strong interpersonal skills
  • Good command of the English language

Desirable:

  • Familiarity with PCR reaction, cloning
  • Familiarity with DNA handling and purification
  • Familiarity with sequence analysis
  • Experience working with a microorganism

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview at the office with manager, cofounders, HR and the rest of team
  3. References Check
  4. Timing: 2-3 weeks
Apply now

Role

DNA Script is looking for a R&D strain engineering Scientist to strengthen the development and the production of its proprietary enzymes. You will join the enzyme process team composed of 7 scientists and be in charge of the strain engineering and construction/optimization of expression vectors for improved expression of recombinant enzymes in bacteria, under the supervision of the enzyme process group leader.

Your mission will be to improve expression yield for different recombinant enzymes. You will work together with the upstream processing team to validate new strains and/or news expressions vectors at fermentation scale. You will also collaborate with other teams, especially enzyme engineering team to develop and improve DNA Script technology.

Responsibilities

  • Define and execute strategy to engineer host strain and generate optimized expression vectors to improve expression yield of different enzymes
  • Solve difficult problems and troubleshoot molecular cloning
  • Prepare plasmid stocks, analyse sequences data to validate constructs and maintain records for the plasmid and the strain database
  • Evaluate expression of new strain/expression vectors at microplate and shake flask level
  • Conduct and coordinate experiments with high level of excellence to ensure precise and accurate data
  • Perform basic biochemistry analysis to evaluate protein expression
  • Support generation of WIs and technical reports for internal tracking
  • Prepare and communicate experimental outcomes in reports and presentations to technical audiences
  • Participate in routine maintenance and lab safety by following laboratory procedures and good laboratory practices

Qualifications and experience

Essential

  • Holds a Master/Engineer or PhD degree in the field of molecular biology or similar
  • Has +5 years of hands-on experience in molecular biology
  • Experience in plasmid design and with biomolecular techniques: Cloning, PCR, DNA gel electrophoresis, PCR, DNA restriction and ligation
  • Hands-on experience in the production of recombinant proteins using bacterial expression systems in plates and/or flasks
  • Comprehensive understanding of microbial strains, metabolic pathway and genomic
  • Familiarity with protein recombinant expression
  • Excellent oral and written communication skills in English
  • Proactive with excellent team spirit
  • Appreciate lab work in a dynamic and evolving environment

Desirable

  • Experience in soluble/insoluble protein extraction as well as SDS-PAGE analysis
  • Experience in operating bioreactors
  • Good level of French

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview at the office with manager, cofounders, HR and the rest of team
  3. References Check
  4. Timing: 2-3 weeks
Apply now

Mission

DNA Script recherche un(e) stagiaire en biologie moléculaire pour l’équipe Applications. Votre mission sera de tester, développer et optimiser ses produits à base d’ADN synthétique. Vous serez en charge d’exécuter des expériences utilisant les produits développés au sein de l’entreprise afin d’évaluer leur potentiel dans une application de biologie moléculaire et de génomique. Vous contriburez également au développement de nouvelles approches et de nouveaux protocoles à même de changer l’expérience utilisateur dans de nombreux domaines des sciences de la vie. Votre activité et vos résultats auront un impact direct au niveau du développement produit et du marketing.

Responsabilités

  • Réaliser les expériences de biologie moléculaire définies en accord avec les ingénieurs/chercheurs de l’équipe Applications de façon efficace et reproductible.
  • Contribuer à l’analyse des résultats, leur présentation et à l’enregistrement rigoureux de données.
  • Aide organisationnelle du laboratoire
  • Participer au développement et à la validation d’applications utilisant les produits développés par DNA Script ;
  • Appliquer et contribuer au respect des bonnes pratiques de laboratoire

Profil recherché

Qualifications et expériences

Essentielles :

  • Bac+2/3, BTS/DUT/Licence en Biotechnologie / Biologie Moléculaire
  • Bases solides des techniques de biologie moléculaire (Méthodes de purification et de caractérisation des acides nucléiques, PCR, qPCR)
  • Excellentes compétences en communication et relations interpersonnelles, bon esprit d’équipe, le stage implique d’interagir avec de nombreuses personnes travaillant au sein d’équipes différentes
  • Excellentes compétences organisationnelles et analytiques
  • Personnalité motivée avec un fort intérêt pour les nouvelles technologies ; appréciant le développement technologique (CRISPR, digital PCR, NGS…)
  • Bonne maîtrise d’Office (Excel, Word et Powerpoint)
  • Dynamisme, réactivité, rigueur
  • Bon niveau d’Anglais (équipe internationale)

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  • Des avantages CSE
  • Une prise en charge de ton navigo à 50%
  • Des activités tout au long de l’année (petits-déjeuners, afterwork, dîner de Noël, anniversaires, séminaire et plein d’autres surprises !)

Divers

  • Stage situé au Kremlin-Bicêtre (région Parisienne, à 5 minutes de la porte d’Italie)
  • Début du stage: début 2022
  • Gratification: 1200€ brut/mois

Déroulement des entretiens

  1. Un premier entretien avec le hiring manager
  2. Echanges avec l’équipe, un de nos cofounders et les RH
  3. Timing: 2-3 semaines
Apply now

Mission

DNA Script est à la recherche d’un(e) stagiaire pour rejoindre l’équipe d’ingénierie d’Enzymes.
Vous participerez aux activités de l’équipe en termes de développement et d’optimisation d’enzymes afin d’améliorer notre technologie de synthèse enzymatique d’oligonucléotides.

Vous travaillerez plus particulièrement avec un ingénieur de recherche afin de renforcer notre équipe de criblage enzymatique sur un projet spécifique. Vous serez notamment en charge de produire des variants d’enzymes à moyenne échelle (en erlenmeyer), les purifier, les caractériser et les tester pour la synthèse d’oligonucléotides automatisée.

Profil recherché

Qualifications et experience

  • Etudiant en BTS, DUT, Licence, Licence professionnelle en biochimie, biotechnologie ou domaine similaire
  • Connaissances/compétences en biochimie : expression et purification de protéines, enzymologie
  • Rigueur et sens de l’organisation
  • Bon niveau d’anglais

Divers

  • Emploi situé au Kremlin-Bicêtre (région Parisienne, à 5 minutes de la porte d’Italie)
  • Début du stage: février/mars 2022 – Possibilité de CDI à la fin du stage
  • Gratification: 1200€ brut/mois

Rejoindre DNA Script, c’est aussi:

  • Des tickets restaurants Swile
  • Des avantages CSE
  • Une prise en charge de ton navigo à 50%
  • Des activités tout au long de l’année (petits-déjeuners, afterwork, dîner de Noël, anniversaires, séminaire et plein d’autres surprises !)

Déroulement des entretiens

  1. Un premier entretien avec le hiring manager
  2. Echanges avec l’équipe, un de nos cofounders et les RH
  3. Timing: 2-3 semaines
Apply now

The role

The Organic Synthesis Laboratory Technician will be working in the chemistry team to assist the synthesis of nucleosides and nucleotides, one of the key reagents in DNA Script’s technology. Under general supervision and following written protocol and work instruction, your task will be to synthesize and purify nucleosides/nucleotides and derivatives thereof, as well as to prepare nucleotide reagent solutions, and to perform other laboratory tasks assigned. You will perform quality analysis and purifications utilizing high-performance liquid chromatography (HPLC) as well as flash chromatography (FC) while maintaining detailed documentation of all work processes.

Responsibilities

  • Synthesis of nucleosides and nucleotides according to written protocol and work instruction
  • Preparation of nucleotide reagent solutions
  • Maintaining detailed documentation of all work process
  • Participate to the order and inventory of chemicals to maintain stock in the chemistry laboratory
  • Perform maintenance of certain equipment of the laboratory
  • Performing other laboratory tasks assigned by team leader
  • Participating chemistry team meeting and presenting technical report
  • Maintaining laboratory safety practice and keep the lab organized and tidy

Qualifications and Experience

  • Holds a Bachelor degree in the field of Chemistry
  • Familiarity with techniques in general chemistry, including but not limited to laboratory skills, data interpretation from various spectroscopic techniques
  • Experience in multi-step organic synthesis
  • Experience in various analytical and purification methods and instrumentation: pH meter, UV-Vis spectrometer, thin-layer chromatography, flash column chromatography, HPLC
  • Strong record keeping skills and good communication skills
  • Ability to work independently and in a team environment
  • Fluent in English (speaking, reading and writing reports)

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview with the manager, HR and the rest of the team
  3. References Check
  4. Timing: 2-3 months
Apply now

The role:

DNA Script is looking for a talented individual to take up a key role in the Advanced Research team at Kremlin-Bicêtre in Paris. He or she will report to the Director of Advanced Research and be responsible for the research and development of inks to be used in DNA Script’s next generation of DNA printers. The candidate will work in a commercially focused, fast moving and innovative, laboratory-based environment and will need to be organized, proactive, detail-orientated and enjoy problem-solving.

Responsibilities

He/she will be responsible for:

  • Formulating inks and dispersions with suitable properties for enzymatic DNA synthesis,
  • Developing strategies and identifying techniques and tools to characterize ink properties and performance,
  • Supplying inks for enzymatic DNA synthesis,
  • Identifying technology to scale-up production of inks to meet future needs,
  • Generating IP in the area of enzymatic DNA synthesis.

Preferred experience

He/she will:

  • Have a degree or advanced qualification (M.Sc. / Ph.D) in physical chemistry, colloid chemistry, polymer science, surface chemistry, formulation science, materials science or chemical engineering,
  • Preferably possess prior experience of formulating aqueous inks, dispersions and formulations comprising proteins, antibodies, enzymes, nanoparticles, pigments,
  • Preferably have prior experience measuring the properties and behaviour of enzymes and catalysts,
  • Ideally have worked in an industry where proper formulation of ingredients is essential to obtain optimal results (e.g. printing, biopharmaceutical, pharmaceutical, consumer health, cosmetics, nutraceuticals, coatings, foods),
  • Be experienced in the characterization of inks and other types of dispersion using methods such as rheology and light scattering,
  • Be familiar with design of experiments,
  • Be prepared to work with liquid handling tools and other types of automation,
  • Be comfortable writing protocols, progress reports and presenting results in R&D meetings in English,
  • Be organized, proactive, task-orientated, and able to work to deadlines.
  • Be a trouble-shooter providing solutions to technical challenges faced in projects.
  • Communicate key information and recommendations to influence technical decisions and strategy,
  • Enjoy being part of a multidisciplinary, high-performing team.

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview at the office with the manager, HR and the rest of the team
  3. References Check
  4. Timing: 2-3 weeks
Apply now

The role:

DNA Script is looking for a talented individual to take up a key role in the Advanced Research team at Kremlin-Bicêtre in Paris. He or she will report to the Director of Advanced Research and be responsible for making enzymatic synthesis work on DNA Script’s next generation of DNA printers. The candidate will work in a commercially focused, fast moving and innovative, laboratory-based environment and will need to be organized, proactive, detail-orientated and enjoy problem-solving.

Responsibilities

He/she will be responsible for:

  • Running enzymatic DNA synthesis tests on prototype microarray synthesizers,
  • Improving synthesis results through good experimental design and careful experimentation, ∙ Developing and proposing improved protocols and workflows,
  • Simplifying approaches and processes,
  • Identifying and flagging software and hardware issues,
  • Identifying and improving characterization methods,
  • Participating in meetings with external collaborators,
  • Generating IP in the area of enzymatic DNA synthesis.

Preferred experience

He/She will:

  • Be a recent graduate engineer or scientist (Meng / MSc / PhD),
  • Preferably have prior experience in nanoscience and nanoengineering, either the study of physical, chemical, and biological phenomena at the microscale and nanoscale, or synthesis and processing of organic, inorganic, polymer, and hybrid nanomaterials by biological, chemical, and physical methods,
  • Ideally have prior experience of using advanced instrumentation for measurement & characterization purposes and/or manipulation of liquids and materials,
  • Be familiar with design of experiments,
  • Be experienced in the use of software tools for processing data from different analytical methods,
  • Be comfortable writing protocols, progress reports and presenting results in R&D meetings in English,
  • Be organized, proactive, task-orientated, and able to work to deadlines, ∙ Be a trouble-shooter providing solutions to technical challenges faced in projects, ∙ Communicate key information and recommendations to influence technical decisions and strategy,
  • Enjoy being part of a multidisciplinary, high-performing team.

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview at the office with the manager, HR and the rest of the team
  3. References Check
  4. Timing: 2-3 weeks
Apply now

The role

You will join the enzyme engineering team and play a critical role in the continued development of our enzyme engineering platform to evolve proprietary enzyme variants for DNA synthesis technology.
Your mission will be to understand DNA synthesis bottlenecks (sources of synthesis error) and develop novel screening routines that will help to target those bottlenecks and overcome them. You will work with cross-functional departments to understand enzyme requirements and build assays.

Responsibilities:

  • Understand deeply each step of our DNA synthesis process and analysis.
  • Execute and analyze multistep DNA synthesis experiments
  • Design and conduct specific tests to bring out DNA synthesis bottlenecks.
  • Develop new screening assays adapted to the identified bottlenecks
  • Handle the transfer of the assays to the Operation Team for routine integration
  • Perform in depth characterization of the enzymes
  • Evaluate the latest methods and technologies for their potential integration into our screening platform
  • Provide guidance and/or recommendation on mutant selection and synthesis optimization strategies

Qualifications and experience

Essential

  • Masters or PhD Degree in Biology, Biochemistry or Chemistry
  • Experience in screening and novel screen development
  • ‘Hand on’ working experience in the field of enzymology
  • Familiarity with protein handling and purification
  • Familiarity with DNA handling and purification
  • Excellent data analysis skills
  • Strong record keeping skills
  • Sense of humor
  • Good command of the English language

Desirable

  • Experience working on DNA-modifying enzymes
  • Mechanistic/structure-function approach

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview at the office with the manager, HR and the rest of the team
  3. References Check
  4. Timing: 2-3 weeks
Apply now

Mission

DNA Script est à la recherche d’un chef d’équipe DSP pour renforcer le développement et la production de ses enzymes propriétaires. Vous rejoindrez l’équipe R&D de production d’enzymes composée de 8 scientifiques et serez responsable de l’activité de purification sous la supervision du chef de groupe de production d’enzymes. Vous serez en charge d’optimiser le procédé de purification de différentes enzymes à différentes échelles afin d’augmenter le rendement de purification de ces enzymes. Vous aurez à collaborer avec d’autres équipes, en particulier l’équipe d’ingénierie enzymatique, pour développer et améliorer la technologie DNA Script.

Responsabilités

  • Superviser l’équipe DSP composée de trois membres
  • Gérer les activités de purification (production de lots et optimisation)
  • Identifier et mettre en œuvre de nouveaux procédés DSP pour une amélioration continue du rendement et du débit
  • Développer des procédés DSP robustes et soutenir le transfert de procédés vers des partenaires externes
  • Définir la stratégie pour le développement, la mise à l’échelle et l’optimisation du procédé DSP pour plusieurs enzymes
  • Mener des expériences, interpréter les résultats, tirer des conclusions et faire des recommandations pour de futures expériences afin d’atteindre les objectifs du projet
  • Prise en charge de la rédaction de WI, de SOP, de Batch Record et de rapports pour le suivi interne et le transfert de technologie
  • Reconnaître et résoudre les problèmes techniques et évaluer les options pour des problèmes expérimentaux complexes
  • Participer à la maintenance de routine et à la sécurité du laboratoire en suivant les procédures et les bonnes pratiques de laboratoire

Profil recherché

Qualifications et experiences

  • Détenir une maîtrise, un diplôme d’ingénieur ou un doctorat de préférence en biochimie, purification des protéines, biotechnologie ou dans des domaines similaires
  • 8+ ans d’expérience dans la purification de protéines
  • Connaissances théoriques approfondies et expérience pratique des techniques de chromatographie
  • Expérience industrielle dans la mise à l’échelle de la purification à l’échelle pilote/commerciale
  • Compétences démontrées en gestion et en leadership d’équipe scientifique
  • Expérience démontrée dans la gestion de plusieurs projets de développement en parallèle
  • Excellentes compétences en communication orale et écrite en anglais, un bon niveau de français est un plus
  • Proactif avec un excellent esprit d’équipe
  • Apprécier le travail de laboratoire dans un environnement dynamique et évolutif

Déroulement des entretiens

  1. Phone interview with the hiring manager
  2. Day interview with manager, Hr, cofounders and the rest of the team
  3. References check
  4. Timing: 2-3 weeks
Apply now

The role

DNA Script is looking for a dynamic and talented individual to join the System Integration team, in charge of the development of new DNA synthesis process and instrumentation.
With the improvement of the quality of enzymatically synthesized DNA came the opportunity to go further in the applicative field, and in particular the possibility to offer a gene synthesis machine, that would take care of both the synthesis of oligonucleotides and their assembly into longer fragments.

The role will be to automate and optimize a gene assembly workflow on a liquid handling platform. The candidate’s goal will be to adapt existing gene assembly protocols to the platform, taking advantage of its built-in functionalities, or creating new ones if necessary. Ultimately this instrument will become an easy-to-use, flexible and intuitive tool to optimize the assembly protocol in an efficient and robust way. The candidate must be handy, autonomous and rigorous, with a detail-oriented mindset and an appetite for automation.

The position will require a lot of transversal and interdisciplinary communication with the different teams members as well as with other teams to implement research protocols into future products.
This offer is an opportunity to join a rapidly growing company and to have a great opportunity of participating to the development of a new and revolutionary technology that will have far-reaching impact across biological sciences.

Responsibilities

Your missions will be:

  • Full responsibility for maintenance and running of an automated liquid handler, as well as writing of the associated new scripts and methods
  • Full automation of an existing gene assembly protocol on the platform
  • Experimental design for optimization of gene assembly workflow, especially the steps that need adaptation for automation
  • Perform in depth analysis of experimental data, write reports and present results.
  • Regular presentation and reporting across all levels of the company
  • Actively contribute to critical company milestones, with a willingness to work outside immediate area of expertise when required

Preferred experience

Qualifications and experience

Essential

  • Engineering degree in biomedical, biotechnology or automation in link with life science
  • 2 to 5 years of experience in Life science R&D labs or diagnostic developing instrumentation or working on HTS platforms
  • Knowledge in molecular biology and or biotechnology
  • Willingness to work on automated system, such as Hamilton or Tecan liquid handlers,
  • Basic coding skills (python … )
  • Excellent organizational, analytical, and systematic troubleshooting skills
  • Ability to work as part of a multidisciplinary team
  • Good level in English
  • Highly motivated and proactive
  • Excellent communication and interpersonal skills

Desirable

  • Excellent English skills and good French speaking level
  • Experience in molecular biology and in particular DNA handling
  • Advanced coding skills
  • Experience in working with liquid-handling robot
  • Experience in process optimization

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview at the office with manager, HR, cofounders and the team
  3. References check
  4. Timing: 2-3 weeks
Apply now

Mission

Dans le cadre de son développement et de la commercialisation de sa première imprimante de synthèse enzymatique d’ADN, DNA Script recherche un(e) technicien(ne) pour la production et le contrôle qualité des supports solides de synthèse d’ADN.
Intégré à l’équipe de Chimie de Surface, le candidat sera amené à interagir avec de nombreuses équipes de R&D. Il/elle sera un support pour les activités des équipes de R&D en fournissant des nouveaux lots de supports solides selon les protocoles développés dans l‘équipe. Il/elle participera également au contrôle qualité et à la validation des lots de supports solides et des kits de synthèse destinés aux clients de DNA Script.

Nous recherchons une personne dynamique, bien organisée, rigoureuse, ayant le souci du détail, et qui est capable de travailler dans un milieu multidisciplinaire et international.

Responsabilités

  • Préparer les supports solides de synthèse d’ADN pour les équipes de R&D et les futurs clients
  • Participer aux étapes de production des kits de synthèse (pipetage, aliquotage, manipulation d’automates, étiquetage…)
  • Contribuer au développement et à la validation des protocoles de préparation des supports solides
  • Préparer les différents tampons/réactifs nécessaires à la préparation des lots de supports solides et assurer leur contrôle qualité
  • Réaliser les études de stabilité des supports solides
  • Participer à la gestion des stocks de réactifs et de supports solides
  • Appliquer et contribuer au respect des bonnes pratiques de laboratoire et des règles d’hygiène et sécurité

Profil recherché

Qualifications et expérience

Essentielles

  • Bac+2/ Bac +3 licence professionnelle en Chimie
  • 3 à 5 ans d’expérience en R&D ou Production dans une société de biotechnologie
  • Bonne maîtrise du pack Office
  • Grande rigueur et qualité d’organisation
  • Dynamisme, réactivité
  • Aptitude à travailler au sein d’une équipe multidisciplinaire
  • Excellentes compétences en communication et relations interpersonnelles

Souhaitables

  • Première expérience dans une société de biotechnologie et/ou dans un environnement de production
  • Expérience en scale-up de procédés de synthèse
  • Expérience avec la manipulation de biomolécules (protéines/ADN)
  • Expérience avec l’utilisation de spectrophotomètre UV-visible
  • Bon niveau d’Anglais (équipe internationale)

Informations diverses

Poste basé au Kremlin Bicêtre (94) – Ile de France – sortie métro ligne 7
Date d’embauche : ASAP
Contrat : CDI en fonction du profil
Rémunération : à définir selon expérience

Rejoindre DNA Script, c’est aussi:

  • Des tickets restaurants Swile
  • Des avantages CSE
  • Une prise en charge de ton navigo à 50%
  • Une mutuelle Alan 100% digitalisée
  • Une plateforme de formation en illimité !
  • Des activités tout au long de l’année (petits-déjeuners, afterwork, dîner de Noël, anniversaires, séminaire et plein d’autres surprises !)

Déroulement des entretiens

  1. Interview téléphonique avec le futur manager
  2. Day interview dans nos locaux avec le manager, les cofondateurs, RH et le reste de l’équipe
  3. Prise de références
  4. Timing: 2 à 3 semaines

Vous pouvez candidatez directement ici.

Apply now

Opportunity and challenges

We are looking for an experienced Director of Data Science from our R&D team in Kremlin-Bicêtre, south of Paris, FRANCE. We are creating a new team inside R&D to regroup different team members with software, data science and bioinformatics expertise. The Director Data Science will manage this team (4 team members today) and report to the CTO.

This is a unique opportunity to develop a team, build a variety of software tools (image analysis, machine learning, LIMS, sequencing pipeline, molecular biology in silico design) in a dynamic environment. Some of those tools are built to enhance R&D productivity, some others to be part of our products.

Responsibilities:

  • Managing a team of bioinformaticians and data scientists
  • Project management and reporting to senior management
  • Improving LIMS and automation SW for R&D: automated image analysis, Instrument control software support, etc
  • Building Machine Learning algorithm to predict purity of DNA synthesis from sequence
  • Building Next Generation Sequencing pipelines and dedicated sequencing analysis tools.
  • Building DNA design tools for various applications of synthetic DNA (gene assembly, multiplex PCR, amplicon seq, qPCR, etc)

Preferred experience

Experience:

  • Technical leader for 5 years in data science applied to biology / bioinformatics
  • Experience in managing developers and scientists
  • Good understanding of molecular biology (NGS, PCR, qPCR, gene assembly)
  • Knowledge of Agile project management
  • Strong technical expertise in software development, data science and bioinformatics
  • Strong quantitative and qualitative skills; detail-oriented with ability to see the big picture and to work effectively at both high and detailed levels.

Ideal Candidate will have:

  • Start-up mindset – experience in a start-up environment before
  • PhD in bioinformatics + 10 years of experience

Recruitment process

  1. Phone interview with the hiring manager
  2. Day interview at the office with the manager, cofounders, HR and the team
  3. References check
  4. Timing: 2-3 weeks
Apply now

The Mission

DNA Script is looking for an Enzyme QC Scientist to strengthen the development and the production of its proprietary enzymes. You will join the enzyme production team composed of 8 scientists and be in charge of the QC activity under the supervision of the enzyme DSP team leader. You will be responsible for developing, optimizing, validating, and executing appropriate QC tests for enzyme release to support R&D, process development and research grade manufacturing. You will have to collaborate with other teams to ensure the successful technology transfer into manufacturing environment.

Responsibilities

  • Develop and optimize analytical and biochemical assays for enzyme characterization, including HPLC, SDS-PAGE and Western Blot, UV/Vis and Fluorescence Spectroscopy (cuvette and multi-well plate), qPCR
  • Help validation department to realize critical evaluation of test methods in order to define acceptance criteria and to establish test method validation protocol
  • Conduct experiments to validate QC methods following the validation protocol established by the validation department
  • Document and compare testing results against control/specification limits
  • Oversee and/or lead laboratory investigations to evaluate out-of-specification and atypical results within QC test methods, including troubleshooting of invalids and monitoring method performance.
  • Conduct experiments, interpret results, draw conclusions, and recommend options for future experiments to achieve project goals
  • Support generation of WIs, SOPs, and reports for internal tracking, development processes and technology transfer.
  • Present experimental results and data analysis at group meetings as directed
  • Participate in routine maintenance and lab safety by following laboratory procedures and good laboratory practices

Qualifications and experiences

  • Hold a Master/Engineer in the field of chemistry, biochemistry, genetics, cell biology or related field
  • 4+ years of work experience in a Quality Control Laboratory
  • QC analytical method development experience, including assay optimization, assay qualification and validation, assay transfer to production and documentation
  • Strong knowledge of protein biochemistry
  • Attention to detail
  • Ability to learn new methods and systems
  • Appreciate lab work in a dynamic and evolving environment
  • Excellent oral and written communication skills in English, good level of French is a plus

Miscellanous

  • Job located in Kremlin-Bicêtre (Paris area, 5 minutes from Porte d’Italie)
  • Start Date: as soon as possible
  • CDI
Recruitment process
  • Phone interview with manager
  • Day Interview at the office with manager, cofounders, HR and the team
  • References Check
  • Timing: 2-3 weeks
Apply now

The Mission

DNA Script is looking for an Enzyme QC Scientist to strengthen the development and the production of its proprietary enzymes. You will join the enzyme production team composed of 8 scientists and be in charge of the QC activity under the supervision of the enzyme DSP team leader. You will be responsible for developing, optimizing, validating, and executing appropriate QC tests for enzyme release to support R&D, process development and research grade manufacturing. You will have to collaborate with other teams to ensure the successful technology transfer into manufacturing environment.

Responsibilities

  • Develop and optimize analytical and biochemical assays for enzyme characterization, including HPLC, SDS-PAGE and Western Blot, UV/Vis and Fluorescence Spectroscopy (cuvette and multi-well plate), qPCR
  • Help validation department to realize critical evaluation of test methods in order to define acceptance criteria and to establish test method validation protocol
  • Conduct experiments to validate QC methods following the validation protocol established by the validation department
  • Document and compare testing results against control/specification limits
  • Oversee and/or lead laboratory investigations to evaluate out-of-specification and atypical results within QC test methods, including troubleshooting of invalids and monitoring method performance.
  • Conduct experiments, interpret results, draw conclusions, and recommend options for future experiments to achieve project goals
  • Support generation of WIs, SOPs, and reports for internal tracking, development processes and technology transfer.
  • Present experimental results and data analysis at group meetings as directed
  • Participate in routine maintenance and lab safety by following laboratory procedures and good laboratory practices

Qualifications and experiences

  • Hold a Master/Engineer in the field of chemistry, biochemistry, genetics, cell biology or related field
  • 4+ years of work experience in a Quality Control Laboratory
  • QC analytical method development experience, including assay optimization, assay qualification and validation, assay transfer to production and documentation
  • Strong knowledge of protein biochemistry
  • Attention to detail
  • Ability to learn new methods and systems
  • Appreciate lab work in a dynamic and evolving environment
  • Excellent oral and written communication skills in English, good level of French is a plus

Miscellanous

  • Job located in Kremlin-Bicêtre (Paris area, 5 minutes from Porte d’Italie)
  • Start Date: as soon as possible
  • 1 year contract (CDD) – possibility to extend in permanent contract
Recruitment process
  • Phone interview with manager
  • Day Interview at the office with manager, cofounders, HR and the team
  • References Check
  • Timing: 2-3 weeks
Apply now

La Mission

Au sein de DNA Script, la plateforme a pour rôle de synthétiser des oligonucléotides pour diverses applications de biologie moléculaire (aussi bien en interne que pour des collaborations externes), ainsi que de valider les nouveaux protocoles/réactifs, et de réaliser le contrôle qualité des réactifs entrant dans la composition des kits commercialisés.

Ces synthèses, réalisées par voie enzymatique, consistent en une série d’étapes itératives permettant d’ajouter un nouveau nucléotide à chaque cycle (élongation enzymatique, lavages et déprotection de la base ajoutée). Ce protocole doit donc être impérativement automatisé de manière robuste, fiable et précise, pour obtenir des fragments d’ADN de haute qualité.

Les projets de recherche étant de plus en plus nombreux, DNA Script recherche une personne talentueuse pour rejoindre la plateforme de synthèse et ainsi permettre d’augmenter et de diversifier les synthèses proposées.
Le candidat sera un support pour les activités des équipes de R&D. Il/elle aura pour rôle de réaliser les synthèses pour l’ensemble de nos clients internes ou externes, en utilisant différents types de liquid handlers, et devra s’assurer de leur qualité. Il sera amené à interagir avec différentes équipes.

Nous recherchons une personne bien organisée, ayant le souci du détail, qui aime résoudre des problèmes et qui est capable de travailler dans un milieu multidisciplinaire. Le candidat devra avoir un esprit pratique et agile lui permettant de maîtriser les subtilités des systèmes robotiques. Il lui faudra comprendre à la fois la biologie moléculaire sous-jacente aux demandes des équipes et les impératifs de la plateforme afin de trouver le meilleur compromis.

Responsabilités

  • Préparer et réaliser les runs de synthèse sur différents instruments, en sachant s’adapter aux spécificités de chaque demande
  • Réaliser les étapes de PSP (Post Synthesis Process) pour l’ensemble des runs de synthèse, afin de livrer des échantillons conformes aux attentes des utilisateurs, pour leurs applications. Cette étape du process est amenée à évoluer régulièrement avec la diversité du type d’oligonucléotides que nous serons amenés à développer
  • Eventuellement réaliser des runs de synthèse sur le SYNTAX
  • Préparer les différents tampons/réactifs nécessaires et participer à leur QC
  • Assurer une disponibilité élevée des équipements en réalisant des opérations de maintenance préventive (test de dispense, reproductibilité…)
  • Contribuer au développement et à la validation des protocoles de synthèse automatisés ; en fonction du degré d’autonomie du candidat
  • Participer aux études de stabilité et aux étapes de manufacturing nécessaires à la préparation de kits pour usage interne
  • Appliquer et contribuer au respect des bonnes pratiques de laboratoire
  • Contribuer activement à la réalisation des objectifs critiques de la société, notamment en acceptant de travailler en dehors de sa zone d’expertise si nécessaire

Profil recherché

Qualifications et expérience

Essentielles

  • Bac+2/3 en Biotechnologie, Biologie Moléculaire, Chimie
  • 3 à 5 ans d’expérience en R&D (biologie moléculaire, diagnostic ou dans un domaine connexe)
  • Apprécie le travail sur systèmes robotisés et le développement technologique
  • Grande rigueur et qualité d’organisation
  • Dynamisme, réactivité
  • Aptitude à travailler au sein d’une équipe multidisciplinaire
  • Excellentes compétences en communication et relations interpersonnelles
  • Bonne maîtrise d’Excel

Souhaitables

  • Première expérience dans une société de biotechnologie et/ou dans un environnement de production/haut débit avec des systèmes d’automatisation
  • Bon niveau d’Anglais (équipe internationale)
  • Expérience dans les méthodes de biologie moléculaire, la purification ADN/ARN, la caractérisation des acides nucléiques et / ou la synthèse d’acides nucléiques

Informations diverses

  • Poste basé au Kremlin Bicêtre (94) – Ile de France – sortie métro ligne 7
  • Date d’embauche : Fin août-début septembre
  • Contrat : CDD/CDI en fonction du profil
  • Rémunération : à définir selon expérience

Rejoindre DNA Script, c’est aussi:

  • Des tickets restaurants Swile
  • Des avantages CSE
  • Une prise en charge de ton navigo à 50%
  • Une mutuelle Alan 100% digitalisée
  • Une plateforme de formation en illimité !
  • Des activités tout au long de l’année (petits-déjeuners, afterwork, dîner de Noël, anniversaires, séminaire et plein d’autres surprises !)

Déroulement des entretiens

  • Entretien téléphonique avec le manager
  • Entretiens dans nos locaux en présence du manager, des cofondateurs, des RH et du reste de l’équipe
  • Prise de références
  • Timing: 2 à 3 semaines
Apply now

La Mission

DNA Script réalise la synthèse enzymatique de l’ADN de façon cyclique en ajoutant un nucléotide à chaque cycle. Ce procédé itératif nécessite de répéter les mêmes étapes ; l’élongation enzymatique, des lavages, puis la déprotection de la base ajoutée. Ce protocole doit donc être impérativement automatisé de manière robuste, fiable et précise pour obtenir une synthèse de haute qualité pour des fragments d’ADN de plusieurs centaines de nucléotides. DNA Script a donc développé une plateforme de synthèse utilisant des automates, chargée de fournir des fragments d’ADN à l’ensemble des collaborateurs de DNA Script.

Cette plateforme joue un rôle central pour DNA Script en évaluant d’une part les nouveaux réactifs (efficacité, stabilité…) pour les équipes de recherche et d’autre part en fournissant des oligonucléotides de qualité à l’équipe qui développe les applications ainsi qu’à nos collaborations externes.
DNA Script recherche une personne talentueuse pour rejoindre l’équipe de la plateforme de synthèse.
Le candidat sera amené à interagir avec de nombreuses équipes différentes. Il/elle sera un support pour les activités des équipes de synthèse, effectuera les opérations quotidiennes sur la plateforme et réalisera les tests nécessaires à assurer la reproductibilité au jour le jour. Ce travail sera effectué en partie sur des systèmes robotiques de type « liquid handler ».

Nous recherchons une personne bien organisée, ayant le souci du détail, qui aime résoudre des problèmes et qui est capable de travailler dans un milieu multidisciplinaire. Le candidat devra avoir un esprit pratique et agile lui permettant de maîtriser les subtilités des systèmes robotiques. Il lui faudra comprendre à la fois la biologie moléculaire sous-jacente aux demandes des équipes et les impératifs de la plateforme afin de trouver le meilleur compromis.

Responsabilités

  • Préparer et réaliser les runs de synthèse sur différents instruments, en sachant s’adapter aux spécificités de chaque demande
  • Réaliser les étapes de PSP (Post Synthesis Process) pour l’ensemble des runs de synthèse, afin de livrer des échantillons conformes aux attentes des utilisateurs, pour leurs applications. Cette étape du process est amenée à évoluer régulièrement avec la diversité du type d’oligonucléotides que nous serons amenés à développer.
  • Préparer les différents tampons/réactifs nécessaires à l’activité des différentes équipes faisant des synthèses et participer à leur QC
  • Réaliser les opérations quotidiennes de manière efficace et reproductible, assurer une disponibilité élevée des équipements en réalisant des opérations de maintenance préventive (test de dispense, reproductibilité…)
  • Eventuellement réaliser des runs de synthèse sur le SYNTAX
  • Contribuer au développement et à la validation des protocoles de synthèse automatisés ; en fonction du degré d’autonomie du candidat
  • Participer aux étapes de manufacturing nécessaires à la préparation de kit pour usage interne (études de stabilité,
  • Appliquer et contribuer au respect des bonnes pratiques de laboratoire
  • Contribuer activement à la réalisation des objectifs critiques de la société, notamment en acceptant de travailler en dehors de sa zone d’expertise si nécessaire

Profil recherché

Qualifications et expérience

Essentielles

  • Bac+2/3 en Biotechnologie, Biologie Moléculaire, Chimie
  • 3 à 5 ans d’expérience en R&D (biologie moléculaire, diagnostic ou dans un domaine connexe)
  • Apprécie le travail sur systèmes robotisés et le développement technologique
  • Grande rigueur et qualité d’organisation
  • Dynamisme, réactivité
  • Aptitude à travailler au sein d’une équipe multidisciplinaire
  • Excellentes compétences en communication et relations interpersonnelles
  • Bonne maîtrise d’Excel

Souhaitables

  • Première expérience dans une société de biotechnologie et/ou dans un environnement de production/haut débit avec des systèmes d’automatisation
  • Bon niveau d’Anglais (équipe internationale)
  • Expérience dans les méthodes de biologie moléculaire, la purification ADN/ARN, la caractérisation des acides nucléiques et / ou la synthèse d’acides nucléiques

Informations diverses

  • Poste basé au Kremlin Bicêtre (94) – Ile de France – sortie métro ligne 7
  • Date d’embauche : Fin août-début septembre
  • Contrat : CDD/CDI en fonction du profil
  • Rémunération : à définir selon expérience

Déroulement des entretiens

  • Entretien téléphonique avec le manager
  • Entretiens dans nos locaux en présence du manager, des cofondateurs, des RH et du reste de l’équipe
  • Prise de références
  • Timing: 2 à 3 semaines
Apply now