Careers

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General & Administration

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionately impatient people. We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write.” We offer the opportunity of joining a dynamic, international, and highly skilled team in a pioneering startup. Our DNA On Demand platform not only has the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.

Main Responsibilities:

  • Defines and updates business plans for EDS reagents and applications in alignment with the company’s objectives
  • Manage EDS reagents and applications landscape analysis and understanding, including customer needs and requirements, as well as current or emerging technology, application, and industry trends
  • Manage the EDS reagents and applications business, including product and financial performance, as well as forecasting and lifecycle management
  • Represent the commercial organization and the needs of customers as part of the product development process and core team
  • Commercial driver of product launch activities
  • Collaborate with others across the marketing organization on product marketing for on-market products, including messaging, collateral, content, campaigns, and communications
  • Sales, applications, regional marketing, and support training and tools development
  • Develop and foster a DNA Script community, in partnership with others in the organization, as well as with distributors, customers, and broader scientific or lay audiences

Experience:

  • Minimum of Bachelor’s degree in life sciences or a related field, graduate degree (including PhD and/or MBA) preferred
  • 5+ years in life sciences or related industry marketing experience, with preference given to candidates with strong experience in oligo synthesis and related research areas
  • Life sciences or related industry product management and product marketing experience
  • Experience with market research, financial analysis and modeling, strategic planning, product launch go-to-market planning, and lifecycle management
  • Experience in cross-functional teams
  • Experience with Jira SW for project management and coordination
  • Effective time and project management
  • Excellent written, presentation, communication and collaboration skills with experience presenting to diverse scientific and other audiences
  • Travel up to 25%

Miscellaneous

  • Job located in South San Francisco
  • Start date: As soon as possible.
Recruitment process
  • Phone interview with manager
  • Day interview at the office with manager, cofounders, HR and the team
  • References check
  • Timing: around 2-3 weeks
Apply now

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionately impatient people. We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”. We offer the opportunity of joining a dynamic, international, and highly skilled team in a pioneering startup. Our SYNTAX DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have a far-reaching impact across biological sciences.

The Role

We are seeking a commercial operations Manager to help the Sales and Support organization with our CRM, reporting and development of new analytical tools. This person will be responsible for hiring, training and supervising customer service representatives. This person will be an integral part of the commercial team helping to create new tools to increase the visibility and alignment across several functions. Someone who is collaborative, transparent and seeks to create new and improve on existing processes will be a great addition to the DNA Script team.

Responsibilities:

  • Work with Commercial leaders on critical strategic, organizational, and operational projects designed to increase revenue, sales productivity, and operational efficiency
  • Provide thought leadership, perform business analysis, and support execution of high-impact strategic projects and mission-critical initiatives
  • Hire, train and manage Customer service representatives for order entry, and customer communication.
  • Review, improve and develop reports to be used by the commerciateams in support of daily operations, monthly/quarterly metrics and business initiatives
  • Facilitate implementation, development and maintenance of Netsuite CRM functionality in a cross-functional team environment, working closely with contractors and DNA Script teams
  • Develop a Forecasting tool and collaborate with Finance and Sales on monthly forecasting cycles
  • Own quarterly revenue projection process, including model updates and meeting facilitation with key Sales and Operations leadership
  • Lead and or participate on cross-functional teams to develop improved processes and communication in support of business initiatives
  • Identify and implement process improvements with the goal of streamlining Order Entry to Order Fulfillment portion of commercial business process
  • Understands and communicates strategic and tactical directions to ensure consistent and cohesive business objectives interdepartmentally
  • Create and update work instructions and process maps
  • Effectively communicate with manufacturing, logistics, sales, finance, and product marketing groups to support process implementation and improvements
  • Plan and monitor operational initiatives to improve the efficiency and effectiveness of customer care
  • Performs other duties as required

Preferred experience

Requirements:

  • A relevant Bachelors Degree, or a Masters Degree in technical or business related discipline
  • 3+ years’ experience in an operations role
  • Previous experience working in or with Sales, Finance, customer service, order management, field support, or similar groups in an analyst position
  • Previous Life Science or Clinical Industry experience a plus
  • Experience working with ERP and CRM systems. Netsuite knowledge preferred
  • Previous experience developing or running reports using BI tools
  • Experience using Microsoft suite including: Word, Excel, Outlook, Power Point, etc.
  • Strong analytical skills and ability to effectively communicate complex topics concisely
  • Very strong Microsoft Excel experience
  • Ability to collaborate and communicate across all levels of the organization and effectively balance commercial and operational needs
  • Ability to handle multiple tasks, embrace change, and innovate in a fast past environment
  • Ability to handle stressful situations and demonstrate strong problem solving skills
  • Ability to develop and present information to commercial leadership
  • Ability to effectively lead, plan and execute on plans for process improvement

Nice to have & background:

  • Management Experience a plus
  • Experience with Field Service and Case Management activities facilitating metrics development
  • Familiar with ISO13485 quality management system and supporting report development to satisfy tracking and trending of product quality.

Recruitment process

  • Phone Interview with manager
  • Day Interview at the office with manager, HR, cofounders and the team
  • References Check
  • Timing: 2-3 weeks
Apply now

The role

We are looking for an experienced Head of Global Human Resources to lead DNA Script’s human resources. The Head of Global Human Resources will plan, lead, direct, develop, and coordinate the strategy, policies, activities, and staff of the Company’s HR department, ensuring legal compliance and implementation of the organization’s mission. The candidate will be in contact with external recruiters, lawyers, management team to define and coordinate the deployment of the HR strategy across the full Company, including French and US sites. The position reports to the Chief of Staff.

Responsibilities

HR team management

  • Manage an HR assistant in France with day-to-day involvement on operational topics.
  • Build a global HR team.
  • Support, train, grow and make the team autonomous on HR topics.
  • Define and be accountable for the HR budget and KPIs.
  • Define and be accountable for human resource-related data protection and quality policies, including GDPR and any quality framework the company wishes to engage with.

Lead HR operations

  • Help DNA Script grow as a global commercially mature organization.
  • Ensure adhesion to and promotion of the company’s core values: Excellence, Transparency and Goodwill.
  • Define and execute the company’s strategy to identify and hire top performers, including interviewing candidates and coordinating hiring processes.
  • Define and execute the company’s strategy to integrate, incentivize and retain talents, in particular key employees, including animating performance reviews, performing regular career interviews with employees and designing training programs.
  • Define and execute key HR policies and strategies: incentives and compensation, hiring, talent management, training, retention.
  • Build a successful and effective global company culture on all Company sites.
  • Coach team leaders on how to lead and amplify our culture through their actions and leadership.
  • Ensure consistency of practices across all sites, while taking into account local specificities.
  • Review and improve existing human resource processes and policies.
  • Ensure relevant documentation of all human resource-related processes and policies is built and maintained.

HR Administration

  • Ensure all contractual documents are kept up to date, in relationship with the company’s lawyers and General Counsel.
  • Be accountable for the correct implementation and continuous improvement of disciplinary and termination processes.
  • Lead relationships with employee representatives and unions, in particular the CSE (Comité Social et Economique) for all French sites.
  • Lead all mandatory and optional negotiations with employee representatives and unions.
  • Define and be accountable for global compensation policies.
  • Oversee the organization of cultural events to strengthen employee’s ownership and satisfaction.

Qualifications and experience

Essential

  • Master’s degree in Human Resources.
  • At least five years of experience as a Head of Human Resources in a global organization.
  • At least five years of experience in high-growth environments.
  • Excellent command of the English language.
  • A proven experience in team and project management at operational level.
  • Demonstrated experience in managing relationships with employee representatives and unions.
  • Strong analytical and problem-solving skills.
  • Excellent verbal and written communication skills.
  • Excellent organizational skills and attention to detail.
  • Excellent reporting skills.
  • Excellent time management skills with a proven ability to prioritize and meet deadlines; ability to efficiently mobilize external resources and coordinate projects.
  • Proficient with Microsoft Office Suite or related software.

Desirable

  • Experience in a biotechnology environment.
  • Start-up mindset.
  • Experience in a scale up environment.
  • Experience in coaching (soft skills, leadership, management, etc.)

Recruitment Process

1- Phone interview with manager

2- Day interview at the office with manager, HR, cofounders and the team

3- References Check

4- Timing: 2 – 3 weeks

Starting date: ASAP

Apply now

The Role

We are seeking a Sales Executive in the West coast of US for a field sales-based position responsible for the territory sales plan. The Territory Account Manager will have strong technical knowledge in Molecular biology applications and will demonstrate technical credibility to effectively consult with customers to influence key decisions on technology and product choices. Strong business acumen is required to build successful account and territory plans and translate territory strategy into business results. The ideal candidate will have a strong history of account relationships with key thought leaders in the Next Gen Sequencing, PCR, qPCR and Sanger Sequencing space.

Responsibilities

  • Demonstrates technical credibility to consult with customers on technology solutions.
  • Demonstrates funnel management skills with strong hunting/prospecting and closing skills.
  • Commitment to rigorous territory planning, market knowledge, both accurate and timely forecasting.
  • Develops and manages to a business plan to meet or exceed business goals for the territory.
  • Understands scientific project needs and business needs of the customer to win the business.
  • Consistently and accurately manages sales process including sales forecasting, pipeline management, and sales tracking using the CRM system and other designated IT tools.
  • Develops and maintains current knowledge of genetic analysis markets, products, and buying practices required to effectively compete in the assigned territory.
  • Utilizes product and application knowledge across the genetic analysis portfolio to successfully conduct selling presentations.
  • Assists in the identification and recruitment of new salespeople as required.
  • Ensure that customers are fully satisfied.
  • Represent the company professionally, ethically, and morally at all times.

Requirements

  • Start-up mind-set.
  • Bachelor’s degree in Biology, Molecular Biology, Biochemistry, or related field; or the equivalent knowledge and experience.
  • Minimum of 3-5 years sales experience in Life Science, with capital equipment experience.
  • Strong desire to win business and establish long term customer relationships.
  • Extensive knowledge of Molecular biology techniques.
  • Ability to travel as needed to be successful in this field-based role.

Nice to have skills & background:

  • A Master’s or PhD degree is desirable.
  • Key account management experience a plus

Miscellaneous

  • Job location: West Coast US, preference in San Francisco bay area
  • Requires travel among DNA Script corporate offices and client sites throughout Western US
  • Start date: Q2 2021
  • Contact: kfe@dnascript.co
Apply now
Manufacturing Operations

Opportunity and challenges

We are looking to assemble a team of best-in-class, innovative and passionate people. We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”. We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

DNA Script is actively searching for a Supply Chain Coordinator who will report directly to the Manufacturing Operations Director.
You will be responsible for ensuring daily follow-up and creating a world class customer service experience as you input to and execute the Customer Service Strategy. You will work in close collaboration with Manufacturing Operations, Product Development and Sales, Field Services and Support and all internal services.

The position will be based in Paris.

Responsibilities :

  • Improve customer service experience, create engaged customers and facilitate organic growth
  • Take ownership of customers issues and follow problems through to resolution
  • Managing the timely and accurate processing of inbound requests from customers
  • Set a clear mission and deploy strategies focused towards that mission
  • Develop service procedures, policies and standards
  • Analyzing and summarizing customer feedback and requests for changes
  • Propose ways of improving customer satisfaction; optimisation of processes, devices, tools, etc.
  • Keep accurate records and document customer service actions and discussions
  • Analyse statistics and compile accurate reports
  • Recruit, mentor and develop customer service agents and nurture an environment where they can excel through encouragement and empowerment
  • Keep ahead of industry’s developments and apply best practices to areas of improvement
  • Control resources and utilise assets to achieve qualitative and quantitative targets
  • Adhere to and manage the approved budget
  • Maintain an orderly workflow according to priorities

Experience :

  • Bachelor degree in Medical/Biotech Engineering or equivalent
  • Proven working experience as a Customer Service Manager, Retail Manager or Assistant Manager
  • Experience in medical device or Life science tool
  • Experience in providing customer service support
  • Able to demonstrate a history of managing project in a technical or scientific context
  • Excellent knowledge of management methods and techniques
  • Working knowledge of customer service software, databases and tools (ideally NetSuite)
  • Strong sense of service: analytical and thinking skills to formulate the best responses to customers
  • Strong client-facing and communication skills
  • Ability to think strategically and to lead
  • Advanced troubleshooting and multi-tasking skills
  • Excellent presentation
  • Awareness of industry’s latest technology trends and applications
  • Fluent in English
Recruitment process
  • Phone interview with manager
  • Day interview with manager, cofounders, HR and the team
  • References Check
  • Timing: 2-3 weeks
Apply now
Product Development

Opportunity and Challenges

We are in the process of assembling a team of best-in-class, innovative and passionate individuals to join our Technical Support team. We want to leverage talents, skills and expertise to achieve one goal: unlock the power of “DNA-write”. We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup company. Our SYNTAX ™ DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

This is an opportunity to join a rapidly growing company and to have a large impact as a product expert supporting a technology that will have a far-reaching impact across biological sciences.

The Role

DNA Script is actively searching for an accomplished Field Applications and Product Support Scientist to build and foster positive relationships and support our partners and customers in their use of DNA Script commercial technologies and related applications. The individual will be responsible for managing customer engagement and delivering expert product support to customers and providing quick resolutions to complex technical inquiries including troubleshooting, coordinating customer feedback/interactions, and representing user experiences within the company to aid development of next generation products. Additionally, the person filling this role is responsible for providing feedback for the development of applications using DNA Script products in novel applications.
You will also play a key role to ensure product issues are documented to facilitate the continuous improvement of our products.

Responsibilities:

Applications Support and Customer Engagement

  • Working closely with sales in customer engagement activities by providing on site and/or remote scientific consultation to customers in both pre- and post-sale opportunities; guiding discussions, and performing product demonstrations, applications-focused training, and assay optimizations.
  • Interface with the product development and applications teams in the use of DNA Script products in applications to meet customer needs.
  • Diagnose and resolve product performance problems fielded directly from customers and staff.
  • Develop and provide training for customers and staff on company products and novel application workflows.
  • Resolve customer complaints related to biochemistry, assay or experimental design, software, instruments, or user’s technical skill.
  • Responsible for relationship management, understanding customer goals, setting appropriate product and performance expectations.

Technical Product Support

  • Uses in-depth technical or scientific knowledge and product expertise to resolve product support escalations. May interact directly with customers or provide deep support internally to Field Service Engineers, Remote Engineers, or customer call center personnel.
  • Writes and updates product user documentation.
  • Collaborate with internal experts by obtaining assistance on challenging cases and sharing product support information.
  • Support the delivery of fully integrated solutions, which may include peripherals, communications, operating systems and applications software.
  • Provide voice of customer, user-oriented and service-related inputs to ongoing and new product development projects.
  • Document product support cases and assist with the development of an internal product support knowledge base for use by customers and the internal support team.
  • Update product support documentation including, but not limited to, User Guide and Frequently Asked Questions (FAQs). Author product information notifications as needed.
  • Identify product quality improvements using support data documented during customer and service interactions and communicate to stakeholders.

Experience:

  • Ph.D or Master’s degree preferred within life science, engineering or related fields — e.g. Biomedical Engineering, Molecular Biology, Genomics, NextGen Sequencing, Analytical biochemistry, Biotechnology or similar.
  • 5+ years of work experience in a technical product support role, research & development role or similar position.
  • Proven experience interacting with researchers at all levels with life science and genomics applications.
  • Previous experience in training, oral presentations and technical writing/editing.

Ideal Candidate will have:

  • Experience with Molecular Biology, Next Gen Sequencing, PCR, qPCR and related innovative technologies/application, including DNA synthesis experience, or utilization of synthetic oligos in biochemical applications.
  • An extensive network and track record interfacing with key opinion leaders within the scientific community.
  • Experience or expertise with Laboratory Automation solutions (eg. pipetting robots, electronics and linear actuators) and systems involving reagents, consumables and related system software.
  • Detailed technical orientation, with robust analytical and organization skills, problem solving, troubleshooting capabilities and negotiation skills.
  • Capability to precisely document issues, root cause analyses, troubleshooting experimentation and resolutions/repairs for complex scientific instrumentation.
  • Proven experience working directly with a field service engineering team.
  • Experience developing, testing and supporting product applications in the laboratory.
  • Proven experience with developing and delivering effective product/technical training.
  • Prior experience using customer relationship management tools to document product support interactions with customers.
  • Customer advocate, solutions-oriented mindset and business orientation.
  • Excellent written and verbal communication skills, presentation skills and technical writing.

Miscellaneous

  • The ideal candidate will be located in the San Francisco Bay Area, however remote candidates within the United States will be considered.
  • May require occasional travel to customer sites and corporate offices.
  • Start date: Q2 2021.

Recruitment process

Phone interview with manager
Day interview at the office with manager, HR, cofounders and the team
References Check
Timing: around 2-3 weeks

Apply now

Opportunity and Challenges

We are in the process of assembling a team of best-in-class, innovative and passionate individuals to join our Technical Support team. We want to leverage talents, skills, and expertise to achieve one goal: unlock the power of “DNA-write”. We offer the opportunity of joining a dynamic, international, and highly skilled team in a pioneering startup company. Our SYNTAX ™ DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

This is an opportunity to join a rapidly growing company and to have a large impact as a product expert supporting a technology that will have a far-reaching impact across biological sciences.

The Role

DNA Script is actively searching for an accomplished Principal/Senior Scientist is responsible for effective and timely resolution of customer cases, including complaint investigations, case documentation, trending analysis and preparing reports, ensuring regulatory compliance and customer satisfaction. Will be responsible for providing technical and troubleshooting support for DNA Scripts Syntax System remotely by phone, email, and other remote support tools. Understands customers’ problems and recommends solutions to meet their needs. The ideal candidate has strong technical knowledge, expertise of primer based molecular workflows and automation system functionality, enjoys troubleshooting, has a problem-solving mindset and prior complaint handling experience.

Responsibilities:
Applications Support and Customer Engagement

  • Responsible for the timely case management of individual cases (Inquiries & Complaints) according to ISO Quality system requirements including creation, acceptance, classification, investigation, complete documentation, and resolution of cases.
  • Triage, monitor and follow up on customer communications using a customer relationship management database system.
  • Interface with internal teams when necessary, to escalate and resolve more complex cases.
  • Ensures, by collaboration and interfacing with stakeholders and global functions, that appropriate technical input and recommendations are communicated to Country Organizations ensuring that the customer is provided with a resolution or workaround in a timely manner.
  • Assist in the development of technical support tools and publications.
  • Accountable for providing information from cases to update product documentation.
  • Accountable for timely communication of quality related product information to cross functional key stakeholders, including Country Organizations.
  • Accountable for regular peer review of escalated cases and providing feedback and guidance to other case owners on expected documentation practices.
  • Oversees complaint databases to identify and report recurring issues to quality management and product development.
  • Performs case-related trending to understand the scope of an issue.
  • Performs regular reviews of case handling and documentation quality, analyzes feedback on customer satisfaction to permanently optimize processes to increase quality and efficiency standards with a focus on customer, compliance, and continuous improvement.

Technical Product Support

  • Writes and updates product user documentation.
  • Collaborate with internal experts by obtaining assistance on challenging cases and sharing product support information.
  • Support the delivery of fully integrated solutions, which may include peripherals, communications, operating systems and applications software.
  • Determine if customer complaint is best resolved via dispatch of field service and facilitate the handoff of issues to the field service team.
  • Provide advice to field service engineers to assist in the resolution of issues.
  • Provide voice of customer, user-oriented and service-related inputs to ongoing and new product development projects.
  • Update product support documentation including, but not limited to, User Guide and Frequently Asked Questions (FAQs). Author product information notifications as needed.
  • Identify product quality improvements using support data documented during customer and service interactions and communicate to stakeholders.

Experience:

  • Bachelor’s or Master’s degree within life science, engineering or related fields — e.g. Biomedical Engineering, Molecular Biology, Genomics, NextGen Sequencing, Analytical biochemistry, Biotechnology or similar.
  • 5+ years of work experience in a technical product support role, research & development role or similar position.
  • Proven experience interacting with researchers at all levels with life science and genomics applications.
  • Previous experience in training, oral presentations and technical writing/editing.

Ideal Candidate will have:

  • Detailed technical orientation, with robust analytical and organization skills, problem solving, troubleshooting capabilities and negotiation skills.
  • Prior experience using customer relationship management tools to document product support interactions with customers.
  • Worked with a field service organization supporting scientific instrumentation or medical devices.
  • Capability to precisely document issues, root cause analyses, troubleshooting experimentation and resolutions/repairs for complex scientific instrumentation.
  • Knowledge of varied regulatory requirements and quality practices, especially in the area of complaint management (e.g., 21 CFR 820.198, ISO 10002, ISO 9001, ISO 13485)
  • Experience with Molecular Biology, Next Gen Sequencing, PCR, qPCR and related innovative technologies/application, including DNA synthesis experience, or utilization of synthetic oligos in biochemical applications.
  • Experience or expertise with Laboratory Automation solutions (eg. pipetting robots, electronics and linear actuators) and systems involving reagents, consumables and related system software.
  • Prior experience using customer relationship management tools to document product support interactions with customers.
  • Customer advocate, solutions-oriented mindset and business orientation.
  • Excellent written and verbal communication skills, presentation skills and technical writing.

Miscellaneous

  • The ideal candidate will be located in the San Francisco Bay Area, however remote candidates within the United States will be considered.
  • May require occasional travel to customer sites and corporate offices.
  • Start date: Q2 2021.
Recruitment process
  • Phone interview with manager
  • Day interview at the office with manager, cofounders, HR and the team
  • References check
  • Timing: around 2-3 weeks
Apply now

The Role

We are looking to assemble a team of best-in-class, innovative and passionate people.  We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”.  We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

DNA Script is actively searching for a Senior Front-end Software Engineer to implement the web-based Lab Information Management System.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences. 

Responsibilities:

  • Design and develop e-commerce application supporting our business and product needs.
  • Work with product management and marketing to capture and define software requirements and influence overall product implementation direction.
  • Work closely with UX design personnel, clients and potential customers to understand their needs, objectives, and use cases, and develop applications meeting these specifications.
  • Strong technical leadership skills  with the ability to solve complex problems.
  • Constant quality improvement of code and infrastructure.

Requirements:

  • A Bachelor’s Degree, or a Master’s Degree in software engineering or related field.
  • 5+ years of software development in an e-commerce environment with various web-based applications, web store, inventory, order management, analytical reports, etc.
  • Prior experience developing and launching web-based SaaS on AWS and/or stand-alone software package.
  • Experience developing web applications using TypeScript, ReactJS, Apollo, and GraphQL (or JSON) API.
  • Experience integrating with third party solutions via web services API.
  • Experience with Atlassian applications including BitBucket, Jira, Confluence, and other 3rd party development tools and utilities.
  • Self-motivated, self-starting, an attention to detail and a great team player.
  • The highest level of personal honesty, integrity and commitment; unquestionably walks the talk so others want to follow.
  • Strong communication skills.

Ideal Candidate will have:

  • Familiarity with enterprise NGS cloud-based systems, ideally Illumina / Design Studio
  • Background in biological sciences, DNA applications, either from education or work experience.

Miscellaneous

  • Job located in Paris, France
  • Start date: ASAP 
Apply now

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionate people.  We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”.  We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

The Role   

DNA Script is actively searching for an accomplished Field Service Engineer to support our partners and customers in their use and application of DNA Script’s commercial product. 

The individual will be responsible for leading complex technical inquiries in the field including troubleshooting and repairs, coordinating customer feedback and interactions, and representing user experiences within the company to aid development of next generation products. 

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have a far-reaching impact across biological sciences.    

The position will be remote based in the San Francisco Bay area and within commuting distance of our South San Francisco, California office.

Responsibilities

  • Installs and optimizes hardware/software/network products and configurations at customer sites.
  • Diagnoses and resolves product performance problems.
  • Performs maintenance and repairs.
  • Documents all field activity performed and ensures timely escalation of difficult issues for quick resolution.
  • Ensures customer satisfaction by advising customers on preventive maintenance and configurations, which may impact product performance.
  • Proactively responds to potential equipment issues to prevent unplanned interruption of customers’ business.
  • Delivers fully integrated solutions, which may include peripherals, communications, operating systems and applications software.
  • Train other field engineers and customers in the company’s system products. 
  • Serve as the primary point of contact for support within the western United States region ensuring all inquiries and complaints are documented, and customers are kept informed of issue resolution. May occasionally be required to provide support in other geographic areas.
  • Provide user-oriented and service-related  input to ongoing and new development projects.
  • Provides support of instrument operations and participates in product training within our South San Francisco  laboratory.
  • Represents DNA Script to customers and ensures customer satisfaction and high-quality service and support experiences. 
  • Ensures customer inquiries, complaints and outcome of service activities are documented in the company’s database.

Experience

  • Bachelors degree within the science field — e.g. biomedical engineering,  analytical biochemistry, biotechnology or similar is highly preferred
  • 4+ years of experience in a similar position and/or experience as an end-user of analytical instrumentation
  • Associates degree within the engineering field (electronics, mechanical) will be considered with 6+ years experience in a similar position working with qPCR instruments and liquid handling robotic systems.

Ideal Candidate will have

  • Experience or expertise with Laboratory Automation solutions (eg. pipetting robots, electronics and linear actuators) and systems involving reagents and consumables
  • Experience with troubleshooting and problem solving. Customer service and solutions-oriented, with capability to precisely document issues, root cause analyses, troubleshooting experimentation and resolutions/repairs.
  • Ability to effectively communicate with customers to ensure understanding of services and troubleshooting performed, as well as ensuring overall customer satisfaction with company products.
  • DNA Synthesis Experience, or Utilization of Synthetic Oligos in a biochemical application.
  • Excellent written and verbal communication skills.
  • Works well in a collaborative team environment but is also able to work independently.
  • Ability to collect technical data and produce high quality and professional presentation materials to communicate data and conclusions internally to stakeholders such as marketing and development teams to transfer knowledge about key field issues.
  • Ability to travel extensively including overnight travel as dictated by business needs

Miscellaneous

  • Remote job based on the West Coast of the USA. Requires up to 75% travel to corporate offices and client sites throughout Western region of the US and other parts of North America.
  • Start date: Q2 2021
Apply now

Opportunity and Challenges

We are looking to assemble a team of best-in-class, innovative and passionate people.  We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”.  We offer the opportunity of joining a dynamic, international and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

DNA Script is actively searching for a motivated and efficient Engineering Technician who will be focused on enabling and testing our DNA synthesis technology and the development of DNA Script’s commercial product. This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.    

The position will be US based, in the South San Francisco, California office.

Responsibilities

  • Work closely with team members to improve quality and performance of mechatronic and automation platforms
  • Perform mechanical, electrical, and fluidic tests on prototypes.  Document results clearly, using approved templates
  • Operate, maintain, and perform advanced service on prototypes.  Address issues in a timely manner.
  • Troubleshoot, repair and requalify prototypes and associated test equipment .
  • Assemble components, subsystems, and systems for testing.
  • Perform operational test and fault isolation on systems and equipment.
  • Assist in determining methods or actions to remedy malfunctions.
  • Assist in the design, construction, test and check-out of test equipment.
  • Use manufacturing, test, development, and/or diagnostic equipment, including, but not limited to, test programs, oscilloscopes, signal generators and specialized test apparatus.
  • Work closely with development engineers to conduct engineering tests, collect performance data, and/or assist in research work.
  • Maintain a clean work environment including instruments and equipment and workspace

Experience

  • Bachelor’s degree in engineering discipline with 1 year of experience

Ideal Candidate will have

  • Experience with instruments including electromechanical systems, especially linear actuators and fluidics.
  • Extensive experience diagnosing and correcting problems with instruments or equipment.
  • Experience and aptitude with testing light mechanical systems.
  • Familiarity with electrical circuits and power supplies.
  • Ability to follow documented  procedures as well as keep organized lab notebook
  • Experience using mechanical tools to assemble and disassemble instrument components, modules, and full systems
  • Experience working on analytical instruments combining mechanisms, electronics, automation, and fluidics.
  • Hands-on experience with breadboard/prototype builds and automation/fluidics optimization.
  • Ability to troubleshoot electronic circuits.
  • Experience in reliability or life testing. Experience developing fixtures and instrumentation for assembly and testing.

Miscellaneous

  • Job located in South San Francisco
  • Start date: Q2 2021
Apply now
Regulatory and Quality

We are looking to assemble a team of best-in-class, innovative and passionate people. We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write”. We offer the opportunity of joining a dynamic, international, and highly skilled team in a pioneering startup. Our Next-Hour DNA Synthesis platforms not only have the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

DNA Script is actively searching for a Quality and Regulatory Affair Director who will report directly to the CEO and be responsible of the creation and the management of all activities related to quality and regulatory. You will define procedures, advise operational departments, and guarantee the regulatory and quality compliance of products at each stage of their development, from concept to delivery.
In this context, you work closely with the various departments of the company (R&D, Product Development, Manufacturing, Marketing, Sales, Management) and the service providers.

Responsibilities

Strategy and build-up of activity

  • Build-up the Regulatory and Quality team and activities;
  • Create and maintain quality procedures, documentation and processes for the Company to operate at gold standard from industry stand-point;
  • Lead and be responsible for product certification in different regulatory frame-work and regions, in-line with Company strategy and objectives;
  • Lead the team in place (one engineer) to complete projects according to established timelines and needs, and develop the team in France and in the US;
  • Have a comprehensive knowledge of the product and its life cycle to analyze product characteristics and to review processes, objectives and constraints within each department;
  • Identify and analyze the regulatory framework and the modalities of introduction to the European and US markets for the product. Study the ISO 9001 and ISO 13485 certifications applicable in the company, as well as the internal quality objectives required by the Management team;
  • Define, propose and put in place the Regulatory and Quality strategy to the Management team for current and new product projects, by developing several iterations taking into account the risks and trends.

Quality

  • Define and implement the QMS system and software;
  • Create quality control tools and develop procedures;
  • Provide guidance and train each department to the quality rules and procedures;
  • Analyze performance indicators and manage incidents;
  • Manage audits and relations with certifying organisms;
  • Be responsible for identifying impacts of international regulations, standards and guidance to our Quality Management System.

Regulatory Affairs

  • Propose and lead a strategy regarding regulatory frame work, Company and product certification;
  • Provide guidance and training to explain the objectives of the regulatory provisions and define the procedures within the departments;
  • Control the respect of protocols;
  • Collect from the departments the information and technical documentation necessary for the preparation of registration, authorization or declaration files, as well as for CE marking. Lead preparatory meetings;
  • Lead and be responsible for all the certification process, relation with certification bodies and fillings;
  • Ensure that authorizations are obtained within the regulatory deadlines and those required by the sales objectives;
  • Control compliance (finished product, documentation, communication). Authorize the launching of batches;
  • Carry out studies and manage audits with service providers.

Qualifications and experience

Essential

  • Masters’ Degree in Medical/Biotech Engineering, Pharmacy or equivalent,
  • At least 8 years of experience in Regulatory Affairs and Quality Assurance environment, preferably with background in Biological Sciences,
  • Experience in the build-up of a Regulatory and Quality department,
  • Demonstrated management or supervisory experience with strong interpersonal and influencing skills,
  • Experience in ISO certifications (ISO 13485, ISO 9001, etc.) and CE marking,
  • Experience in medical device or Life science tool,
  • Excellent written and oral communication skills with a strong emphasis on organizational capabilities and external communications,
  • Demonstrated flexibility and adaptability in carrying out various assignments in a concrete way,
  • Operational and concrete problem-solving mindset,
  • Excellent written and verbal communication skills,
  • Strong organization and analysis/problem skills,
  • Strong attention to detail/quality focus,
  • Familiarity with Quality concepts and practices,
  • An in-depth knowledge of European and International regulations,
  • Fluent in English.

Desirable

  • Start-up mind-set is strongly preferred,
  • Understanding of the product introduction,
  • Experience in GMP.

Recruitment process

  • Phone interview with manager
  • Day interview with manager, cofounders, HR and the team
  • References check
  • Timing: around 2-3 weeks

You can also apply directly here.

Apply now
Research & Development

The role

DNA Script is looking for a dynamic and talented individual to join the Synthesis and NGS Platform team, in charge of the development of new DNA synthesis process and protocols.
Enzymatic synthesis of an oligonucleotide is an exciting new technology for which still a lot of optimization is needed. Detailed NGS and molecular based methods such as qPCR are essential to constantly improve the technology.
Within DNA Script, most of the enzymatically synthesized oligos and genes are characterized by NGS. To increase the understanding of our processes and keep improving the quality of our enzymatic synthesis, new characterization tools need to be implemented to assess the oligos perfect functionality in a variety of applications.

DNA Script is looking for a Molecular Biology Engineer to join the Next-Generation Sequencing (NGS) and Biological Characterization team within DNA Script Synthesis Platform.
The candidate will be working on the development and optimization of characterization methods for DNA Script nucleic acid-based products (for example qPCR, TaqMan assay). He/she will be responsible for the automation of classical molecular biology applications to demonstrate and validate the functionality of DNA Script oligos in a robust, reliable, and reproducible way. He/she must have a solid molecular biology background to propose routine-compatible methods and to deeply characterize DNA Script nucleic acids.
As part of the NGS team, the candidate must be able to perform semi-automated library preps and launch runs when needed to ensure the continuous activity of the NGS platform as well as the standard analysis.

He/she will be directly involved in the reporting of DNA Script product performances and contribute to their improvement. The position will require a lot of transversal and interdisciplinary communication with the synthesis team as well as with other R&D teams to understand our technology and implement molecular tools to validate future products applications.

This offer is an opportunity to join a rapidly growing company and to have a great opportunity of participating to the development of a new and revolutionary technology that will have far-reaching impact across biological sciences.

Responsibilities

Your missions will be:

  • Develop and optimize molecular biology protocols for the characterization of DNA Script products.
  • Automate these new protocols to save time, simplify control and increase reproducibility.
  • Perform the required experiments and reliably document and report those experiments.
  • Perform in depth analysis of experimental data, write reports and present results.
  • Perform semi-automated NGS library preps to ensure functioning of the NGS platform.
  • Collaboration with R&D partners to develop and to provide appropriate experiments to specific needs.
  • Make regular presentation and reporting across all levels of the company.
  • Engage in good laboratory/documentation practices, write Standard Operating Procedures (SOPs) and enforce their correct use.
  • Actively contribute to critical company milestones, with a willingness to work outside immediate area of expertise when required.

Qualifications and experience

Essential

  • Master’s or Engineering degree in the field of molecular biology, biotechnology or similar.
  • 2 to 5 years of experience in molecular biology.
  • Strong knowledge of usual and advanced molecular biology techniques: DNA/RNA purification and characterization methods, PCR, qPCR, sequencing technologies (NGS), molecular probes …
  • Down-to-earth mindset focused on finding simple solutions to complex problems.
  • Willingness to work on automated system, such as EpMotion and Opentrons.
  • Excellent organizational, analytical, and systematic troubleshooting skills. Rigorous with a high attention to details.
  • Ability to work as part of a multidisciplinary team. Excellent communication and interpersonal skills.
  • Good level in English
  • Highly motivated and proactive.

Desirable

  • Experience in automation, use of liquid handling systems.
  • Having basic coding skills (Python), or willing to learn for NGS data analysis and Opentrons programming.
  • Experience in nucleic acid synthesis.
  • Experience in process optimization.
  • Excellent English skills and good French speaking level

Miscellaneous

  • Job located in Kremlin-Bicêtre (Paris area)
  • Contract: CDI/CDD depending on profile
  • Start date: ASAP

Recruitment process

  • Phone interview with manager
  • Day interview at the office with manager, cofounders, HR and the team
  • References check
  • Timing: around 2-3 weeks
Apply now

Le rôle

DNA Script recherche une personne dynamique et talentueuse pour rejoindre l’équipe System Integration, chargée du développement de nouveaux procédés et instruments de synthèse d’ADN.
La synthèse enzymatique d’un oligonucléotide est un processus cyclique, basé sur l’ajout un à un de nucléotides par une ADN polymérase qui ne nécessite aucune matrice d’ADN. Ce processus itératif doit être automatisé de manière robuste, fiable et précise pour obtenir une synthèse de haute qualité.

Le rôle consistera à diriger le développement et l’optimisation du processus de synthèse enzymatique de l’ADN, une activité centrale de l’entreprise. Le candidat mènera rigoureusement des études de développement pour améliorer la qualité des oligos de synthèse d’ADN en termes de pureté, de quantité et de fonctionnalité. Il ou elle sera entièrement responsable d’une plateforme automatisée dédiée aux activités de développement de synthèse, en assurant son fonctionnement et son amélioration continue.

Le candidat doit avoir une solide formation en biologie moléculaire, être débrouillard, habile et apprendre rapidement pour saisir avec précision les subtilités de la technologie et développer efficacement les systèmes automatisés de synthèse. Le poste nécessitera beaucoup de communication transversale et interdisciplinaire avec les différents membres de l’équipe ainsi qu’avec d’autres équipes pour mettre en œuvre les protocoles de recherche des futurs produits.

Cette offre est une opportunité de rejoindre une entreprise en pleine croissance et avoir la chance de participer au développement d’une nouvelle technologie révolutionnaire qui aura un impact considérable sur les sciences biologiques.

Responsabilités

Vos missions seront les suivantes :

  • Être entièrement responsable du pilotage et du fonctionnement d’un système robotique pour la manipulation de liquides (Liquid handler, Tecan ou Hamilton), des instruments développés en interne et de l’écriture de nouveaux scripts et méthodes associés.
  • Proposer et développer de nouveaux protocoles pour gagner du temps, simplifier le contrôle, augmenter la reproductibilité et minimiser les erreurs du système.
  • R & D sur les protocoles de synthèses : proposition d’amélioration, mise en place des plans d’expérience, (choix des paramètres, et analyses, optimisation des paramètres de synthèse : nouvelle formulation de réactif ou nouveau procédé.
  • Effectuer une analyse approfondie des données expérimentales, rédiger des rapports et présenter les résultats.
  • Collaborer avec des partenaires externes pour développer de nouvelles applications innovantes pour notre technologie.
  • Faire des présentations et des rapports réguliers à tous les niveaux de l’entreprise.
  • Contribuer activement aux étapes clés de l’entreprise, avec la volonté de travailler en dehors du domaine d’expertise immédiat si nécessaire.

Profil recherché

Qualifications et expérience

Indispensables

  • Diplôme d’ingénieur ou doctorat dans le domaine de la biotechnologie/biologie moléculaire.
  • 2 à 5 ans d’expérience minimum.
  • Excellente connaissance de la biologie moléculaire et/ou de la biotechnologie et en particulier de la manipulation de l’ADN/ARN.
  • Volonté de travailler sur des systèmes automatisés, tels que les robots manipulateurs de liquides Hamilton ou Tecan,
  • Avoir des compétences de base en codage (Python), ou être prêt à apprendre.
  • Excellentes capacités d’organisation, d’analyse et de troubleshooting.
  • Capacité à travailler au sein d’une équipe multidisciplinaire.
  • Bon niveau d’anglais
  • Grande motivation et proactivité
  • Excellente communication et relations interpersonnelles

Souhaitables

  • Excellentes compétences en anglais et bon niveau de français
  • Expérience dans le travail avec la polymérase, l’ADN et/ou l’ARN
  • Expérience de l’utilisation des plans d’expérience (Jump)
  • Expérience de travail avec des robots de manipulation de liquides tels que Hamilton.

Déroulement des entretiens

  • Interview téléphonique avec le manager
  • Day Interview dans nos locaux avec le manager, les cofondateurs, les RH et le reste de l’équipe
  • Prise de références
  • Timing: 2 à 3 semaines
Apply now

Le rôle

DNA Script est à la recherche de son Analytical Team Leader pour rejoindre l’équipe Analytics et diriger sa plateforme analytique qui représente une partie importante de l’équipe de développement. Aujourd’hui, la plateforme analytique de DNA Script a deux missions principales :

  • Une mission de service : analyse de tous les oligonucléotides synthétisés et de certains réactifs clefs, principalement par UHPLC-MS (HR-MS Q-ToF (Agilent), LC-MS Simple Quadrupole (Waters)) et électrophorèse capillaire.
  • Une mission de développement et d’amélioration continue des techniques analytiques répondant aux besoins quotidiens et spécifiques de tous les membres de l’équipe R&D, tels que l’analyse de très petites quantités ou de très longs oligonucléotides ou d’oligo modifiés.

Le candidat dirigera l’équipe Analytics, une équipe de quatre personnes talentueuses. Le Team leader gérera les opérations quotidiennes, en veillant à l’utilisation optimale de l’instrumentation, en gérant les priorités et en limitant les temps d’arrêt.
Il assurera au quotidien la haute qualité analytique des résultats, fera des suggestions et apportera des améliorations aux méthodes existantes, proposera de nouvelles solutions analytiques complémentaires pour augmenter la capacité analytique et répondre aux besoins analytiques futurs.

La plateforme analytique étant centrale pour les équipes R&D, le candidat devra interagir avec différentes équipes, comprendre leurs besoins et développer des solutions analytiques appropriées. Il proposera, développera et validera, en collaboration avec son équipe, de nouvelles méthodes analytiques, en LC-MS et électrophorèse capillaire.
Le Team Leader consolidera les données provenant de plusieurs méthodes analytiques afin de fournir une image analytique complète de nos oligos.

Nous recherchons une personne rigoureuse, méthodique, bien organisée et soucieuse du détail. La personne doit également être capable de résoudre des problèmes et de jouer un rôle transversal au sein d’une équipe pluridisciplinaire, et dispose d’excellentes capacités de communication.

Responsabilités

  • Gérer une équipe de quatre personnes possédant un large éventail de compétences.
  • Gérer le parc d’équipements analytiques avec l’aide de l’équipe (contrats de réparation et de maintenance, benchmark et processus d’achat de nouveaux équipements, pipeline d’analyse de données et améliorations …).
  • Développer des méthodes analytiques pour les projets de R&D (préparation des échantillons, méthodes d’analyse, méthode de quantification, etc.), consolider les données de plusieurs méthodes analytiques, donner une vue d’ensemble en fournissant des rapports complets aux non-spécialistes.
  • Être responsable de la qualité des résultats analytiques, fournir des indicateurs clés de performance et des mesures pour évaluer la qualité des résultats et les limites des méthodes.
  • Travailler en étroite collaboration avec la plate-forme de synthèse pour développer de nouvelles méthodes analytiques à haut débit pour la caractérisation des oligonucléotides et des contaminants.
  • Communiquer les résultats en réalisant des présentations, en rédigeant des rapports et des SOPs.
  • Réaliser régulièrement une veille bibliographique sur des nouvelles méthodes analytiques innovantes, se tenir informé des nouveaux produits commerciaux et modernisations/améliorations.

Profil recherché

Qualifications et expérience

Indispensables

  • Expérience en management de 5 ans d’une équipe d’analystes
  • Doctorat en chimie analytique (spectrométrie de masse/électrophorèse capillaire) ou diplôme d’Ingénieur (Senior avec 10+ ans d’expérience dans ce domaine)
  • Solides compétences en matière d’organisation et de communication interpersonnelle
  • Aptitude avérée dans l’analyse de biomolécules, de préférence des oligonucléotides.
  • Bonne connaissance des techniques UPLC-MS et MS/MS et/ou de l’électrophorèse et des logiciels associés.
  • Capacité à concevoir, exécuter, interpréter et troubleshooting
  • Excellente communication orale et écrite
  • Grande motivation, passionné par le développement d’outils et de méthodes
  • Capacité à travailler de manière indépendante et au sein d’une grande équipe multidisciplinaire
  • Excellent niveau d’anglais et bon niveau de français

Souhaitables

  • Expérience en analyse MS ou électrophorèse d’oligonucléotides
  • Expérience avec LIMS
  • Expérience dans un laboratoire accrédité ISO 13485
  • Expérience en électrophorèse capillaire ou autres méthodes analytiques

Déroulement des entretiens

  • Interview téléphonique avec le manager
  • Day Interview dans nos locaux avec le manager, les cofondateurs, les RH et le reste de l’équipe
  • Prise de références
  • Timing: 2 à 3 semaines
Apply now
Equipe Applications

DNA Script recherche un(e) Technicien(ne) en biologie moléculaire pour l’équipe Applications. Votre mission sera de tester, développer et optimiser ses produits à base d’ADN synthétique. Vous serez en charge d’exécuter des expériences utilisant les produits développés au sein de l’entreprise afin d’évaluer leur potentiel dans différents types d’applications de biologie moléculaire et de génomique. Votre travail contribuera également au développement de nouvelles approches et de nouveaux protocoles à même de changer l’expérience utilisateur dans de nombreux domaines des sciences de la vie. Votre activité et vos résultats auront un impact direct au niveau du développement produit et du marketing et seront cruciaux dans l’établissement de partenariats scientifiques et commerciaux.

Responsabilités

  • Réaliser les expériences de biologie moléculaire définies en accord avec les chercheurs de l’équipe Applications de façon efficace et reproductible.
  • Contribuer à la conception des expériences, à l’analyse des résultats et leur présentation.
  • Participer au développement et à la validation d’applications utilisant les produits développés par DNA Script ;
  • Contribuer à la rédaction de notes d’applications par la production de rapports d’expérience de qualité ;
  • Contribuer à la mise au point et à la rédaction des SOPs (protocoles d’utilisation) et en s’assurant de leur mise en application au sein de l’équipe ;
  • Appliquer et contribuer au respect des bonnes pratiques de laboratoire
  • Participer activement à la réalisation des objectifs critiques de la société, notamment en acceptant de travailler en dehors de sa zone d’expertise si nécessaire
Profil recherché

Qualifications et expériences

Essentielles :

  • Bac+2/3 en Biotechnologie ou Biologie Moléculaire
  • 3 à 5 ans d’expérience en R&D en biologie moléculaire dans le secteur industriel ou académique
  • Excellente connaissance des techniques de biologie moléculaire (Méthodes de purification et de caractérisation des acides nucléiques, PCR, qPCR, ddPCR, techniques de séquençage (Sanger, NGS), techniques d’édition de génomes (CRISPR…), CHIP, molecular probes)
  • Excellentes compétences en communication et relations interpersonnelles, le poste implique d’interagir avec de nombreuses personnes travaillant au sein d’équipes différentes
  • Excellentes compétences organisationnelles et analytiques
  • Personnalité motivée avec un fort intérêt pour les nouvelles technologies ; appréciant le travail sur automates et le développement technologique
  • Bonne maîtrise d’Office (Excel, Word et Powerpoint)
  • Dynamisme, réactivité
  • Bon niveau d’Anglais (équipe internationale)

Souhaitables:

  • Expérience de travail sur des systèmes automatisés de type robots pipeteurs (Eppendorf, Tecan, Opentrons)
  • Expérience de travail au sein d’équipes pluridisciplinaires
  • Expérience dans le domaine de la synthèse d’acides nucléiques
  • Expérience dans le séquençage d’acide nucléiques (Sanger ou NGS, préparation de librairie de séquençage)
Déroulement des entretiens
  • Interview téléphonique avec le manager
  • Day interview dans nos locaux avec le manager, RH, les cofondateurs et le reste de l’équipe
  • Prise de références
  • Timing: 2 à 3 semaines

Apply now

The role

DNA Script is looking for a dynamic and talented individual to join the System Integration team, in charge of the development of new DNA synthesis process and instrumentation.
Enzymatic synthesis of an oligonucleotide is a cyclic process, based on a one by one addition of nucleotides by a DNA polymerase that requires no DNA template. This iterative process needs to be automated in a robust, reliable, and precise way to achieve high quality synthesis.

The role will be to lead the development and optimization of enzymatic DNA synthesis process, a core activity of the company. The candidate will rigorously conduct development studies to enhance the quality of DNA Script oligos in terms of purity, quantity, and functionality. He or she will be fully responsible for an automated platform dedicated to synthesis development activities, ensuring its functioning and continuous improvement. The candidate must have a solid molecular biology background, be handy and a quick learner to accurately grasp the subtilities of the technology, and efficiently troubleshoot automated systems. The position will require a lot of transversal and interdisciplinary communication with the different team members as well as with other teams to implement research protocols into future products.

This offer is an opportunity to join a rapidly growing company and to have a great opportunity of participating to the development of a new and revolutionary technology that will have far-reaching impact across biological sciences.

Responsibilities

Your missions will be:

  • Full responsibility for maintenance and running of an automated synthesis liquid handler, internally developed instruments and the writing of associated new scripts and methods.
  • Propose and develop new protocols to save time, simplify control, increase reproducibility, and minimize system errors.
  • Experimental design for optimization of synthesis reaction parameters: new reagent formulation (based on design of experiment, screening…) or new process.
  • Perform in depth analysis of experimental data, write reports and present results.
  • Collaboration with external partners to develop new innovative application for our technology.
  • Regular presentation and reporting across all levels of the company
  • Actively contribute to critical company milestones, with a willingness to work outside immediate area of expertise when required.

Qualifications and experience

Essential

  • Engineering degree or PhD in the field of biotechnology, molecular biology.
  • 2 to 5 years of experience.
  • Excellent knowledge in molecular biology and or biotechnology and in particular in DNA /RNA manipulation.
  • Willingness to work on automated system, such as Hamilton or Tecan liquid handlers,
  • Having basic coding skills (Python), or willing to learn
  • Excellent organizational, analytical, and systematic troubleshooting skills
  • Ability to work as part of a multidisciplinary team.
  • Good level in English
  • Highly motivated and proactive
  • Excellent communication and interpersonal skills

Desirable

  • Excellent English skills and good French speaking level
  • Experience in working with polymerase, DNA and /or RNA
  • Experience in process optimization
  • Experience in working with liquid-handling robot such as Hamilton
Recruitment process
  • Phone interview with the manager
  • Day interview at the office with manager, HR, cofounders and the team
  • References check
  • Timing: 2-3 weeks
Apply now

The role

DNA Script is looking for a talented Analytical Team leader to lead its Analytics platform which is an important part of the Development team. Today, DNA Script’s analytical platform has two main missions:

  • A mission of service by analyzing all the synthesized oligonucleotides and proprietary reagents of the R&D teams, mainly by UHPLC-MS (HR-MS Q-ToF (Agilent), LC-MS Simple Quadrupole (Waters)) and capillary electrophoresis.
  • A mission of development and continuous improvement of analytical techniques responding to the daily and specific need of all the R&D team members, such as analyzing very small quantities or very long oligonucleotides.

The candidate will lead the analytical team, a team of four talented persons. The team leader will manage day to day operation, ensuring optimum use of instrumentation, managing priorities, and limiting down time.

He/she will ensure day to day high analytical quality of results, provide suggestions and improvements to existing methods, propose new complementary analytical solutions to increase analytical capacity and to address future analytical needs.

As the analytics platform is central to R&D teams, the candidate will have to interact with many different teams, understand their needs and develop appropriate analytical solutions. He/she will, in collaboration with his team, propose, develop, and validate new analytical methods, in LC-MS and capillary electrophoresis. The analytical team leader will consolidate data from several analytical methods to provide a complete analytical picture of our oligos.

We are looking for a person who is rigorous, methodical, well organized, detail-oriented, problem-solver and capable of playing a cross-functional role within a multidisciplinary team with excellent communication skills.

Responsibilities

  • Manage a team of four with a wide range of expertise.
  • Manage the analytical equipment parc with the help of the team, (repair and maintenance contracts, new equipment benchmarking and buying process, data analysis pipeline and improvements ….)
  • Develop analytical methods for R&D projects (sample preparation, methods of analysis, quantification method, etc.), consolidate the data from several analytical method, provide with team the big picture providing comprehensive reports to non-specialists.
  • Be accountable of the analytical results quality, provide KPI and metrics to assess result quality and method limitations.
  • Work in close relationship with the synthesis platform in developing new high throughput analytical methods for oligonucleotides and contaminants characterization.
  • Communicate results by performing presentations, writing reports and SOPs.
  • Perform regular state of the art studies on new innovative analytical methods, stay informed on new commercial products and upgrade.

Qualifications and experience

Essential

  • Management experience of 5 years of an analytical team
  • PhD in Analytical Chemistry (Mass Spectrometry/Capillary Electrophoresis) or Senior Engineer with 10+ years of relevant experience
  • Strong organizational and interpersonal communication skills
  • Demonstrated aptitude in biomolecule analysis, preferably oligonucleotides
  • Good knowledge of UPLC-MS and MS/MS techniques and/or electrophoresis and associated software.
  • Ability to design, execute, interpret, and troubleshoot experiments
  • Excellent verbal and written communication
  • Highly motivated, passionate about developing tools and methods
  • Ability to work independently and within a large multidisciplinary team
  • Excellent level of English and good level of French

Desirable

  • Experience in MS analysis or electrophoresis of oligonucleotides
  • Experience with LIMS
  • Experience in an ISO 13485 accredited laboratory
  • Experience in Capillary Electrophoresis or other analytical methods

Miscellaneous

  • Job located in Kremlin-Bicêtre (Paris area, 5 minutes from Porte d’Italie)
  • Start date: ASAP
Recruitment process

Phone interview with manager
Day Interview at the office with manager, cofounders, HR and the team
References check
Timing: around 2-3 weeks

Apply now

The role

DNA Script is looking for a a dynamic, talented individual to join the Nucleotide Chemistry team for an internship in modified nucleotides project. The project consists of multistep synthesis of different modified nucleotide targets. Those modified nucleotides will be tested in our technology (enzymatic DNA synthesis) in purpose to synthesize modified DNA for several application such as epigenetic, fluorescence probe. The internship will be supervised by a confirmed PhD in organic chemistry.

Qualifications and experience

Essential

  • Last year of engineering/ master degree in the field of organic chemistry
  • Good knowledge and practice in organic reaction, purification utilizing chromatography techniques (FC and HPLC) and analysis of organic molecules by TLC, NMR, HPLC, LC/MS
  • Ability to work as part of a large multi-disciplinary team
  • Good understanding and speaking of English
  • Excellent learning, organizational skills
  • Highly motivated candidate with passion for science

Miscellaneous

  • Job located in Kremlin-Bicêtre (Paris area)
  • Start date: to be determined

Apply now

Your Mission

DNA Script is looking for a talented scientist to take up a key role within the Applications team. He or she will be in charge of defining, developing and managing various projects to support the development of the company core technology. He or she will be responsible for interacting with internal and external partners to provide with thoroughly qualified oligonucleotides for their applications, to evaluate use and performances of oligos for various current applications and develop new application for the technology. This includes testing nucleic acid molecules in various set-ups and challenge with conventional chemistry synthetized oligos. This platform will play a central role for DNA Script by demonstrating the ability of Syntax and EDS technology to provide oligonucleotides that can be used for all current and future research applications.

To perform these tasks, the candidate will need to interact with many different teams, in particular the Bioinformatics team that will provide the oligonucleotide designs and perform analytics, the Synthesis platform that will produce the starting oligonucleotides and the NGS platform that will analyse the sequences. A technician hiring is planned in a near future to assist on projects.

We are seeking an individual who is well organized, proactive, detail-orientated, enjoys problem-solving, and able to work in a multi-disciplinary role.

Responsibilities

  • Define project outlines, experimental plans, perform experimentations and results analysis of a broad variety of assays based on EDS.
  • Develop and optimize methods based on nucleic acids manipulations.
  • Ensure efficient and reproducible day to day operations, provide high quality results, ensure high equipment uptime, manage team and resources (equipment, reagents, consumables),
  • Work collaboratively with groups across the company to set up appropriate projects.
  • Perform in-depth analysis of experimental data,
  • Engage in good laboratory/documentation practices, write Standard Operation Protocols (SOPs) and enforce their correct use,
  • Actively contribute towards critical company milestones, with a willingness to work outside immediate area of expertise where required.

Qualifications and experience

Essential:

  • Holds a PhD degree in the field of molecular biology/ biotechnology,
  • Minimum of 5 years’ experience in R&D after PhD graduation in managing challenging research projects in the field of cancer,
  • Experience of application development in an industrial environment,
  • Very comfortable/happy at the bench,
  • Highly experienced in molecular biology methods including methods of purification and characterisation of nucleic acids, PCR, qPCR, sequencing methods (Sanger, NGS), gene editing technologies (CRISPR…)
  • Excellent organisational, analytical, and systematic troubleshooting skills,
  • Excellent communication, reporting and interpersonal skills,
  • Positive experience of management of technicians or engineers,
  • Used to build, animated and managed scientific collaboration within an academic or private environment.
  • Highly motivated, pro-active, with a passion for developing tools and methods,
  • Ability to work independently and as part of a large multi-disciplinary team,
  • Dynamic with positive attitude willing to engage at a very high level,
  • Excellent English language level as well as at least an intermediate French language level.

Desirable:

  • Proven experience in the development of innovative processes.
  • Experience in nucleic acid handling (automated) and single cell technology.

Recruitment Process

Phone interview with manager
Day Interview at the office with manager, HR, cofounders and the team
References Check
Timing: 2-3 weeks

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The role: 

DNA Script is looking for a talented individual to take up a key role in the Advanced Research team at Kremlin-Bicêtre in Paris. He or she will report to the Director of Advanced Research and be responsible for developing, characterizing and supplying solid supports for use in Advanced Research projects. To perform these tasks, the candidate will need to be organized, proactive, detail-orientated, enjoy problem-solving, and be able to work in a multi-disciplinary environment.

Responsibilities

He/she will be responsible for:

  • Sourcing planar solid supports (glass, plastic and silicon) with appropriate characteristics (e.g. optical transparency, flatness) and modifications (e.g. fiducial markings, electrodes),  
  • Investigating chemistries to immobilize DNA on said solid supports in different locations and at different densities in a robust manner,
  • Investigating passivation methods to protect against sticking of reagents used in DNA synthesis,
  • Characterizing said supports with different techniques (e.g. contact angle, microscopy, ellipsometry), 
  • Determining the surface behaviour of said solid supports with repeated exposure to liquids used in DNA synthesis (e.g. wetting, robustness),
  • Developing ways to cleave DNA from said supports in an efficient manner that are appropriate for downstream applications,
  • Optimizing said supports based on feedback from synthesis tests performed by colleagues,  
  • Supplying appropriate modified solid supports to colleagues,
  • Streamlining the production of solid supports and developing methods of batch manufacture. 

Qualifications and experience

He/she will:

  • Have a degree or advanced qualification (M.Sc. / Ph.D) in a relevant subject (e.g. surface chemistry, physical chemistry, colloid and polymer chemistry),  
  • Possess prior experience of modifying glass, plastic and silicon (ideally planar) solid supports for bioapplications (e.g. in vitro diagnostics, next generation sequencing),
  • Be comfortable writing protocols, progress reports and presenting results in R&D meetings in English,
  • Be organized, proactive, task-orientated, and able to work to deadlines. 

Recruitment process

1- Phone interview with manager
2- Day interview with manager, cofounders, HR and the team
3- References check
4- Timing: around 2-3 weeks

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The role

DNA Script is looking for a talented individual to take up a key role within the Applications team. He or she will be in charge of developing and managing the platform dedicated to produce nucleic acid assemblies based on the company’s enzymatic technology to manufacture de novo synthetic nucleic acids and novel assembly techniques. This platform will play a central role for DNA Script by demonstrating the ability of Syntax and EDS technology to provide oligonucleotides that can be used to produce any targeted synthetic gene.

The candidate will be in charge of implementing the full process of synthetic gene/nucleic acid assembly, from the reception of orders, oligonucleotide design, assembly production, sequencing analysis, QC and customer delivery. He or she will implement the specific assembly strategy defined by the R&D Assembly principal scientists in a given project. In addition, the candidate will be responsible of transferring the protocols developed by the R&D Assembly scientists in the Applications team and adapt them to the Assembly platform in a robust automated way.

To perform these tasks, the candidate will need to interact with many different teams, in particular the R&D Assembly scientists in the Applications team that will develop the assembly protocols and define the assembly strategy for a given project, the Bioinformatics team that will provide the oligonucleotide designs and perform analytics, the Synthesis platform that will produce the starting oligonucleotides and the NGS platform that will analyse the assembled sequences. He or she will be assisted by a technician.

We are seeking an individual who is well organized, proactive, detail-orientated, enjoys problem-solving, and is able to work in a multi-disciplinary role.

Responsibilities

  • Develop and manage an automated Assembly Platform: Ensure efficient and reproducible day to day operations, provide high quality results, ensure high equipment uptime, manage team and resources (equipment, reagents, consumables), 
  • Work collaboratively with groups across the company to set up appropriate projects
  • Perform in-depth analysis of experimental data, 
  • Effectively document and report on platform KPI, QC data and processes,
  • Engage in good laboratory/documentation practices, write Standard Operation Protocols (SOPs) and enforce their correct use,
  • Actively contribute towards critical company milestones, with a willingness to work outside immediate area of expertise where required.

Qualifications and experience

Essential

  • Process or biotechnology engineering, PhD or similar,
  • Minimum of five years’ experience in managing a service platform, preferentially in the field of molecular biology, 
  • Experience in molecular biology methods including PCR, restriction digestion, DNA/RNA purification, and nucleic acid characterisation and/ or in nucleic acid synthesis.
  • Experience in automation, liquid handlers, high throughput screening or analysis, 
  • Excellent knowledge of Excel and other Microsoft Tools, 
  • Excellent organisational, analytical, and systematic troubleshooting skills,
  • Excellent communication and interpersonal skills, 
  • Highly motivated, with a passion for developing tools and methods, 
  • Ability to work independently and as part of a large multi-disciplinary team,
  • Dynamic with positive attitude willing to engage at a very high level, 
  • Excellent English language level as well as at least an intermediate French language level.  

Desirable

  • Experience in following or implementing quality systems such as ISO 9001 or ISO 13485.
  • Experience in coding with Visual Basic Script (VBS), python or the like. 
  • Knowledge on gene assembly protocols

Recruitment process

1- Phone interview with manager

2- Day interview with manager, cofonders, HR and the team

3- References check

4- Timing: 2 to 3 weeks

The offer is available here: https://www.welcometothejungle.com/fr/companies/dna-script/jobs/biotechnology-platform-manager_le-kremlin-bicetre

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La mission 

DNA Script recherche un ingénieur en mécanique afin de participer à la conception (CAO), l’assemblage, les essais et la maintenance des prototypes qui seront nos futurs produits ou pour nos fabrications internes de réactifs. 

Les instruments automatisés utilisés par DNA Script mettent en œuvre les outils habituels de la robotique (motorisations, transmissions, guidages, capteurs, chauffage, électronique simple (arduino) et codage (Python, VB …) ainsi que des fonctions annexes mais essentielles de thermique, de mélange ou de micro-fluidique (dispense précise de liquide de quelques µl, valves, pompes…). 

Vous serez chargé de concevoir, de réparer ou de modifier tous nos automates en recherche et développement en leur ajoutant de nouvelles fonctions thermiques, optiques, fluidiques ou mécaniques et fonctions des demandes des chercheurs. 

Vous évoluerez au sein d’une équipe multidisciplinaire de chercheurs en biologie, d’ingénieurs en intégration système qui travailleront avec vous pour tester et améliorer vos réalisations de façon dynamique, rapide et efficace. Votre activité et vos résultats auront un impact direct au niveau du développement des futurs produits dans l’amélioration des produits actuels et des procédés de fabrication. Bien que très technique la mission demande une bonne compréhension des phénomènes physiques, fluidiques, thermiques, mis en jeu dans les instruments concernés.

Responsabilités 

  • Conception générale (mécanique, électronique, fluidique, thermique) d’instruments automatisés
  • Dimensionnement mécanique et électromécanique de pièces et de systèmes 
  • Réalisation de travaux d’assemblage et d’ajustage mécanique, câblage électrique, programmation simple électronique 
  • Test des assemblages, tests fonctionnels et contrôles des spécifications
  • Suivis des approvisionnements : commandes des pièces, suivi des sous-traitances, gestion des pièces de rechanges 

Expériences et compétences 

Requises 

  • Ecole d’ingénieur spécialité ou mécanique robotique :  ENSMM Besançon, INSA mécanique, SUPMECA, UTC Compiègne, UTT Troyes, IFMA Clermont….
  • 10 ans d’expérience dans la conception et réalisation de système automatisé pour le diagnostic, ou les sciences de la vie, ou machines spéciales 
  • Connaissance et pratique des circuits électroniques pour la commande des robots
  • Bon communiquant, compréhension des demandes non techniques et traduction en système
  • Travail d’équipe, bonne réactivité, débrouillard et créatif

Souhaitables 

  • Anglais courant 

Informations diverses 

  • Poste basé au Kremlin-Bicêtre (Paris)
  • Contrat : CDI
  • Début : ASAP

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Mission

DNA Script is looking for a R&D DSP Team Leader to strengthen the development and the production of its proprietary enzymes. You will join the enzyme production team composed of 8 scientists and be in charge of the purification activity under the supervision of the enzyme production group leader. You will be in charge of optimizing the purification process of different enzymes at different scale in order to increase the purification yield of those enzymes. You will have to collaborate with other teams, especially enzyme engineering team, to develop and improve DNA Script technology.

Responsibilities

  • Supervise DSP team composed of three members
  • Manage operational activities of purification area (production and optimization)
  • Identify and implement new downstream technology/instrumentation for continuous improvement of yield and throughput
  • Develop robust downstream process and support process transfer to external partners
  • Define strategy for the development, scale-up and optimization of the DSP process for multiple enzymes
  • Conduct experiments, interpreting results, drawing conclusions and recommending options for future experiments to achieve project goals
  • Support generation of WIs, SOPs, batch records and reports for internal tracking, technology transfer and development processes.
  • Recognize and resolve technical problems and evaluate options for complex experimental problems
  • Participate in routine maintenance and lab safety by following laboratory procedures and GLP

Qualifications and experiences

  • Hold a Master/Engineer degree or PhD preferably in biochemistry, protein purification, biotechnology or related fields
  • 8+ years of experience in proteins purification
  • Extensive theoretical knowledge and hands-on experience with chromatography techniques
  • Industrial experience in purification scale-up at pilot/commercial scale
  • Demonstrated management and leadership skills of scientific team
  • Demonstrated experience with managing multiple development projects in parallel
  • Excellent oral and written communication skills in English, good level of French is a plus
  • Proactive with excellent team spirit
  • Appreciate lab work in a dynamic and evolving environment

Miscellaneous

  • Job located in Kremlin-Bicêtre (Paris area, 5 minutes from Porte d’Italie)
  • Start Date: as soon as possible
  • Contact: send your resume to jl@dnascript.com
Apply now